Learn More
universal sequence-dictated positioning reveals a lack of C. elegans A high-resolution, nucleosome position map of service Email alerting click here top right corner of the article or Receive free email alerts when new articles cite this article-sign up in the box at the
Point and regional centromeres specify a unique site on each chromosome for kinetochore assembly. The point centromere in budding yeast is a unique 150-bp DNA sequence, which supports a kinetochore with only one microtubule attachment. In contrast, regional centromeres are complex in architecture, can be up to 5 Mb in length, and typically support many(More)
The mechanisms ensuring specific incorporation of CENP-A at centromeres are poorly understood. Mis16 and Mis18 are required for CENP-A localization at centromeres and form a complex that is conserved from fission yeast to human. Fission yeast sim1 mutants that alleviate kinetochore domain silencing are defective in Scm3(Sp), the ortholog of budding yeast(More)
  • Oliver Lemon, Xingkun Liu, Daniel Shapiro, Carl Tollander
  • 2006
We demonstrate the REALL-DUDE system 1 , which is a combination of RE-ALL, an environment for Hierarchical Reinforcement Learning, and DUDE, a development environment for " Information State Update " dialogue systems (Lemon and Liu, 2006) which allows non-expert developers to produce complete spoken dialogue systems based only on a Business Process Model(More)
A number of different approaches have been applied to the treatment of errors in spoken dialogue systems, including careful design to prevent potential errors, methods for on-line error detection, and error recovery when errors have occurred and have been detected. The approach to error handling presented here is premised on the theory of grounding , in(More)
We demonstrate a new development environment 1 for " Information State Update " dialogue systems which allows non-expert developers to produce complete spoken dialogue systems based only on a Business Process Model (BPM) describing their application (e.g. banking, cinema booking, shopping, restaurant information). The environment includes automatic(More)
In this article we describe how Java can be used to implement an object-based, cross-domain, mixed initiative spoken dialogue manager (DM). We describe how dialogue that crosses between several business domains can be modelled as an inheriting and collaborating suite of objects suitable for implementation in Java. We describe the main features of the Java(More)
Advanced spoken dialogue systems incorporate functionalities such as mixed-initiative and cross-domain dialogues. In this paper an object-based approach to cross domain dialogue modelling is described in which service agents representing primary transaction types and support agents representing tasks such as eliciting payment details are selected as(More)
We demonstrate a web-based environment for development and testing of different pedestrian route instruction-giving systems. The environment contains a City Model, a TTS interface, a game-world, and a user GUI including a simulated street-view. We describe the environment and components, the metrics that can be used for the evaluation of pedestrian route(More)
This paper presents some of the main features of a prototype spoken dialogue manager (DM) that has been incorporated into the DARPA Communicator architecture. Developed in Java, the object components that constitute the DM separate generic from domain-specific dialogue behaviour in the interests of maintainability and extensibility. Confirmation strategies(More)