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Throughout life, adult organs continually adapt to variable environmental factors. Adaptive mechanisms must fundamentally differ from homeostatic maintenance, but little is known about how physiological factors elicit tissue remodeling. Here, we show that specialized stem cell responses underlie the adaptive resizing of a mature organ. In the adult(More)
Field measurements were conducted to determine particulate emissions and trace gas emissions, including CO2, CO, CH4, NMHCs, NOx, NH3, N2O, and SO2, from open burning of wheat straw and maize stover, two major agricultural residues in China. The headfire ignition technique was adopted, and sampling was performed downwind from the agricultural fire.(More)
Smart-card-based password authentication scheme is one of the commonly used mechanisms to prevent unauthorized service and resource access and to remove the potential security threats over the insecure networks and has been investigated extensively in the last decade. Recently, Chen et al. proposed a smart-card-based password authentication scheme and(More)
Field measurements were conducted in four representative rural areas across China to determine carbonaceous aerosol emissions from combustion of household biofuel. Results showed that the size distribution of both black carbon (BC) and organic carbon (OC) peaked at 0.26-0.38 microm. OC accounted for a significant fraction of fine particles from wheat(More)
Transducin (β)-like 1 X-linked receptor 1(TBLR1) is an F-box-like and WD repeat-containing protein which functions as a switch in transcriptional activation, However, the clinical significance and biological role of TBLR1 in breast cancer remains largely unknown. Western blotting, immunocytochemistry and real-time PCR were used to evaluate TBLR1 expression(More)
Adult stem cells are important in replenishing aged cells to maintain tissue homeostasis. Aging in turn may exert profound effects on stem cell's regenerative potential, but to date the mechanisms of such stem cell aging are poorly understood, and it is not clear to what extent stem cell aging contributes to tissue or organ aging. Here we show in female(More)
Hypoxia-inducible factor 1 (HIF-1) mediates a metabolic switch that blocks the conversion of pyruvate to acetyl-CoA in cancer cells. Here, we report that HIF-1α also inhibits fatty acid β-oxidation (FAO), another major source of acetyl-CoA. We identified a PGC-1β-mediated pathway by which HIF-1 inhibits the medium- and long-chain acyl-CoA dehydrogenases(More)
The Raf kinase inhibitor protein (RKIP) is a tumor suppressor that protects against metastasis and genomic instability. RKIP is downregulated in many types of tumors, although the mechanism for this remains unknown. MicroRNAs silence target genes via translational inhibition or target mRNA degradation, and are thus important regulators of gene expression.(More)
Sucrose is the primary photosynthesis product and the principal translocating form within higher plants. Sucrose transporters (SUC/SUT) play a critical role in phloem loading and unloading. Photoassimilate transport is a major limiting factor for seed yield. Our previous research demonstrated that SUT co-localizes with yield-related quantitative trait loci.(More)
A novel label-free immunosensor for the detection of C-reactive protein (CRP) was developed based on a three-dimensional ordered macroporous (3DOM) gold film modified electrode by using the electrochemical impedance spectroscopy (EIS) technique. The electrode was electrochemically fabricated with an inverted opal template, making the surface area of the(More)