Neurofibrillary tangles are aggregates of hyperphosphorylated tau that are one of the pathological hallmarks of Alzheimer's disease (AD). Tau phosphorylation is regulated by a balance of kinase and phosphatase activities. Our previous study has demonstrated that ginsenoside Rd, one of the principal active ingredients of Pana notoginseng, inhibits okadaic… (More)
Although pulsed electromagnetic field (PEMF) exposure has been reported to promote neuronal differentiation, the mechanism is still unclear. Here, we aimed to examine the effects of PEMF exposure on brain-derived neurotrophic factor (Bdnf) mRNA expression and the correlation between the intracellular free calcium concentration ([Ca(2+)]i) and Bdnf mRNA… (More)
As e-commerce is becoming more and more popular, the number of customer reviews for online products grows rapidly. For a popular product, there can be hundreds of reviews. This makes it difficult for a potential customer to read all of them in order to get as much information as possible and to make a decision on purchasing. Therefore, a summarization of… (More)
Alzheimer’s disease (AD) is a complicated neurodegenerative disease which causes memory loss and dementia. Many researchers have revealed the vital roles of β-amyloid proteins (Aβ) in the proceeds of AD. Aβ deposition in AD patients’ brains might function as immune stimulus, and inflammation is believed to play an important role in AD pathologically. We… (More)
Isolation and characterization of microsatellite loci for acorn weevil Curculio bimaculatus Faust (Coleoptera: Curculionidae).