Xingguang Chen

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D-serine is a well-known activator of N-methyl-D-aspartate receptors; however, little is known about the teratogenic effects of D-serine overdose during early embryonic development. Here, we used zebrafish as a model to test toxicity and teratogenicity, since they have transparent eggs, making the organogenesis of zebrafish embryos easier to be observed.(More)
We isolated two zebrafish ankylosis progressive homolog (ankh) genes, ankha and ankhb, from embryonic zebrafish. Amino acid sequences deduced from zebrafish ankh genes are aligned with orthologue proteins from other species, the results showed that they share high percentage of identities (74–82%). Whole-mount in situ hybridization experiments showed that(More)
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