Xinggen Fang

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To access the effect of actual metal coverage rate (MCR) on neointimal growth at covered side branch ostium and stented artery after implantation of a flow diversion device. Flow diverters (FDs) were implanted into abdominal aortas of 20 New Zealand rabbits. Four weeks and three months after FD implantation, the patency of side branches covered by the(More)
A remarkable curing rate has been achieved in the treatment of intracranial intractable aneurysms by using flow-diverting stents (FDS). An appropriate metal coverage (MC) of this device influences the hemodynamics of aneurysm significantly but little to branches in vitro. The MC changes after elongation or compression and the actual changes are still(More)
Endothelial progenitor cells (EPC) are believed to be involved in aneurysmal repair and remodeling. The aim of this study was to test this hypothesis and, if true, explore how EPC contribute to aneurysm repair in a rabbit model of elastase-induced carotid aneurysm. Rabbits were divided randomly into an in situ carotid EPC transfusion group (ISCT group,(More)
PURPOSE The optimal treatment modalities of ruptured middle cerebral artery aneurysm are still controversial. The objective of this study is to analyze the outcomes of patients with ruptured middle cerebral artery aneurysms treated by endovascular coiling. MATERIALS AND METHODS From October 2011 to October 2015, 67 patients with 71 ruptured middle(More)
OBJECTIVE To inspect the role of AMD3100 that acts as an antagonist of SDF-1/CXCR4 on the formation of neointima in rabbit saccular aneurysm after flow diverter (FD) treatment. METHODS Twenty saccular aneurysm models were established by using porcine pancreatic elastase. Three weeks later, a FDs of Tubridge was implanted into the saccular aneurysm. All(More)
Reendothelialization in the aneurysm neck is pivotal to vascular repair for intracranial aneurysm after flow diverter (FD) implantation. Recombinant human stromal cell-derived factor 1α (rhSDF-1α) is a vital chemoattractant to stem cells and potentially facilitates reendothelialization. Here, we sought to investigate the therapeutic effects of intravenous(More)
Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embolization of very small ruptured(More)
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