Xing Zhong Yuan

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Tuberculosis remains second only to HIV/AIDS as the leading cause of mortality worldwide due to a single infectious agent. Despite chemotherapy, the global tuberculosis epidemic has intensified because of HIV co-infection, the lack of an effective vaccine and the emergence of multi-drug-resistant bacteria. Alternative host-directed strategies could be(More)
The concentrations of eight heavy metals (Cu, Zn, Pb, Cd, Cr, Ni, Hg, and As) in the intertidal surface sediments from Quanzhou Bay were determined to evaluate their levels and spatial distribution due to urbanization and economic development of Quanzhou region, southeast China. The ranges of the measured concentrations in the sediments are as follows:(More)
Effective vaccine development for human immunodeficiency virus type 1 (HIV-1) will require assays that ascertain the capacity of vaccine immunogens to elicit neutralizing antibodies (NAb) to diverse HIV-1 strains. To facilitate NAb assessment in peripheral blood mononuclear cell (PBMC)-based assays, we developed an assay-adaptable platform based on a(More)
Previously, adsorption feature of a dirhamnolipid biosurfactant on diverse microbial cells was studied and the effect of the adsorption on cell surface hydrophobicity was compared. In this paper, the adsorption behavior of a monorhamnolipid and a dirhamnolipid on cells of two Pseudomonas aeruginosa strains was investigated in order to further reveal the(More)
In this study, a novel lipid vector has been developed for targeted delivery of oligodeoxynucleotides (ODN) to tumors that overexpress folate receptor. This is based on a method developed by Semple et al. (1), which utilizes an ionizable aminolipid (1,2-dioleoyl-3-(dimethylammonio)propane, DODAP) and an ethanol-containing buffer system for encapsulating(More)
Liver regeneration (LR) is of great clinical significance in various liver-associated diseases. LR proceeds along a sequence of three distinct phases: priming/initiation, proliferation, and termination. Compared with the recognition of the first two phases, little is known about LR termination and structure/function reorganization. A combination of "omics"(More)
Phenolic compounds were classified into different groups based on the structure and functional groups of the phenol. Quantitative structure-activity relationship (QSAR) analysis was performed between the toxicity and octanol/water partition coefficient (logP) for these groups. The results showed that the toxicity of non-ionisable phenols is dependent on(More)
OBJECTIVE To study the correlation of toxicity with biodegradability (BODT) in order to promote QSBR development and understand the degradation mechanism. METHODS Toxicity of substituted phenols to river bacteria was determined by the turbidities that were measured using a spectrophotometer (UV-190) at 530 nm against a blank control. The biodegradability(More)
The traditional cryptographic mechanisms are not enough for wireless sensor networks (WSNs) when the control of sensor nodes are taken by an interior adversary. Trust management system can solve this problem efficiently, and enhance the security and reliability of WSNs. One of the key problems in trust management system is computing trust values of nodes.(More)
Both internal carbon source and some external carbon sources were used to improve the nutrient removal in Anaerobic-Anoxic-Oxic-Membrane Bioreactor (A2/O-MBRs), and their technical and cost analysis was investigated. The experimental results showed that the nutrient removals were improved by all the carbon source additions. The total nitrogen and phosphorus(More)