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Decreased serum brain-derived neurotrophic factor (BDNF) is associated with post-stroke depression but not with BDNF gene Val66Met polymorphism
TLDR
Serum concentrations of BDNF decrease in PSD patients and BDNF may play an important role in the pathogenesis of PSD, however, Val66Met polymorphisms are not associated with serum concentrations ofBDNF. Expand
Intranasal ginsenoside Rb1 targets the brain and ameliorates cerebral ischemia/reperfusion injury in rats.
TLDR
This work suggests that intranasal GRb1 exerts brain-targeting effects and that a single dose of intran asalGRb1 immediately after MCAO ameliorates ischemia/reperfusion insult. Expand
Dynamic change of neutrophil to lymphocyte ratio and hemorrhagic transformation after thrombolysis in stroke
TLDR
NLR is a dynamic variable, and its variation is associated with HT after thrombolysis in stroke patients, and the NLR was higher in patients who developed PH or sICH at 3–6, 12–18, and 36–48 h after IVT. Expand
Is There a Stroke Belt in China and Why?
TLDR
A stroke belt of high stroke incidence exists in 9 provincial regions of north and west China and may be caused, at least in part, by a higher population prevalence of hypertension and excess body weight. Expand
Intranasal administration of nerve growth factor ameliorate β-amyloid deposition after traumatic brain injury in rats
TLDR
Intranasal delivery of NGF provides a potential strategy for reducing the risk of developing AD in the later life of TBI patients. Expand
Subtypes and One-Year Survival of First-Ever Stroke in Chinese Patients: The Nanjing Stroke Registry
TLDR
The significant influence of cardiovascular disease on the first-year survival rate emphasizes the importance of acute stroke management and control of hypertension, DM, AF and other predictors for decreasing case fatality and improving prognosis. Expand
Recurrence after Ischemic Stroke in Chinese Patients: Impact of Uncontrolled Modifiable Risk Factors
TLDR
The recurrence rate is higher in Chinese patients with ischemic stroke compared with the one reported in western populations, and failure to control some modifiable risk factors inChinese patients may be responsible for this discrepancy. Expand
Intranasal nerve growth factor enhances striatal neurogenesis in adult rats with focal cerebral ischemia
TLDR
Investigation of the effect of intranasal NGF on striatal neurogenesis and functional recovery in adult rats with focal cerebral ischemia showed that treatment with IN NGF failed to increase cell proliferation but improved survival of newly generated cells in ipsilateral striatum and subventricular zones (SVZ). Expand
The effect of socioeconomic status on three-year mortality after first-ever ischemic stroke in Nanjing, China
TLDR
Lower SES has a negative impact on the outcome of first-ever stroke in Nanjing, China, and the need to improve preventive and secondary care for stroke among low SES groups is confirmed. Expand
Distal Hyperintense Vessels on Flair: A Prognostic Indicator of Acute Ischemic Stroke
TLDR
Examining the prognostic value of HVs in AIS revealed that distal HVs are an independent predictor of a favorable outcome at 90 days and was correlated with the presence of LMCs. Expand
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