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Territrem and Butyrolactone Derivatives from a Marine-Derived Fungus Aspergillus Terreus
Seventeen lactones including eight territrem derivatives and nine butyrolactone derivatives were isolated from a marine-derived fungus Aspergillus terreus under solid-state fermentation of rice and showed strong inhibitory activity against acetylcholinesterase and evident antiviral activity towards HSV-1. Expand
Insights into Deep-Sea Sediment Fungal Communities from the East Indian Ocean Using Targeted Environmental Sequencing Combined with Traditional Cultivation
This study investigates the fungal community structure in five sediments from a depth of ∼4000 m in the East India Ocean using a combination of targeted environmental sequencing and traditional cultivation to suggest that the deep-sea sediment from the East Indian Ocean can serve as habitats for new fungal communities compared with otherdeep-sea environments. Expand
Diversity and Antimicrobial Activity of Culturable Fungi Isolated from Six Species of the South China Sea Gorgonians
The diversity of culturable fungi associated with six species of healthy South China Sea gorgonians were investigated using a culture-dependent method followed by analysis of fungal internal transcribed spacer sequences, suggesting that the gorgonian-associated fungi may aid their hosts in protection against pathogens. Expand
Exploring fungal diversity in deep-sea sediments from Okinawa Trough using high-throughput Illumina sequencing
It is suggested that Illumina sequencing had been dramatically accelerating the discovery of fungal community of deep-sea sediments by challenging the traditional view that the diversity of Sordariomycetes phylotypes was low in the deep- sea environments. Expand
Nahuoic Acids B-E, Polyhydroxy Polyketides from the Marine-Derived Streptomyces sp. SCSGAA 0027.
Four new polyol polyketides containing a decalin ring, nahuoic acids B-E (1-4), together with a known analogue, nahuoic acid A (5), possessing an unprecedented carbon skeleton, were isolated from aExpand
Cytotoxic dihydrothiophene-condensed chromones from marine-derived fungus Penicillium oxalicum.
Two new dihydrothiophene-condensed chromones and a new natural chromone, namely oxalicumones A-C (1-3), respectively, were isolated from a culture broth of a marine-derived fungus PenicilliumExpand
In Vitro and in Vivo Antitumor Effects of Plant-Derived Miliusanes and Their Induction of Cellular Senescence.
It is revealed that the antiproliferative properties of miliusanes in carcinoma cells were highly associated with the p21-dependent induction of cellular senescence, which is superior to the mainstay chemotherapeutics paclitaxel or fluorouracil. Expand
Diverse Deep-Sea Fungi from the South China Sea and Their Antimicrobial Activity
The results suggest that diverse deep-sea fungi from the South China Sea are a potential source for antibiotics’ discovery and further increase the pool of fungi available for natural bioactive product screening. Expand
Alkaloids from the deep-sea-derived fungus Aspergillus westerdijkiae DFFSCS013.
Two new benzodiazepine alkaloids, circumdatins K and L, two new prenylated indole alkal steroids, 5-chlorosclerotiamide, and one novel amide, aspergilliamide B, together with six known alkaloid were isolated from the deep-sea-derived fungus Aspergillus westerdijkiae DFFSCS013. Expand
Dihydrothiophene-condensed chromones from a marine-derived fungus Penicillium oxalicum and their structure-bioactivity relationship.
Compounds 1-4, 3a-3e, 3g-3h, and 4b showed significant cytotoxicity against several carcinoma cell lines with IC50 ≤ 10 μM and their structure-bioactivity relationship was discussed. Expand