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A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol
ABSTRACT Mycobacterium tuberculosis, the causative agent of tuberculosis, is an intracellular pathogen that shifts to a lipid-based metabolism in the host. Moreover, metabolism of the host lipidExpand
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Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase.
New approaches are required to combat Mycobacterium tuberculosis (Mtb), especially the multi-drug resistant and extremely drug resistant organisms (MDR-TB and XDR-TB). There are many reports thatExpand
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Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis.
Mycobacterium tuberculosis can metabolize cholesterol to both acetate and propionate. The mass of isolated phthiocerol dimycoserate, a methyl-branched fatty acylated polyketide, was used as aExpand
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A new dimeric sesquiterpene and other related derivatives from the marine red alga Laurencia okamurai
Abstract A new Bis-sesquiterpene, Nanji A ( 1 ), has been isolated together with 7 known compounds, debromolaurinterol ( 2 ), laurinterol ( 3 ), laurinterol acetate ( 4 ), isolaurinterol ( 5 ),Expand
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An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders
Previous epigenome-wide association studies (EWAS) of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) have been inconsistent. This may be due to small sample sizes, andExpand
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Synthesis and high thermoelectric efficiency of Zintl phase YbCd2−xZnxSb2
We synthesized a series of polycrystalline YbCd2−xZnxSb2 (x=0, 0.4, 0.8, 1, 1.2, 1.6, and 2) samples and measured their thermoelectric properties. Thermoelectric figure of merit ZT at 700K is higherExpand
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Zintl phase Yb1-xCaxCd2Sb2 with tunable thermoelectric properties induced by cation substitution
It has been shown previously that the thermoelectric properties of the Zintl phase compound YbCd2Sb2 can be finely tuned via Zn substitution at the Cd-site in the anionic (Cd2Sb2)2− framework. HereExpand
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Thermoelectric properties and electronic structure of Zintl compound BaZn2Sb2
Polycrystalline sample of the title compound was prepared and its thermoelectric properties from 2to675K were investigated. This Zintl compound shows rather low thermal conductivity, 1.6Wm−1K−1, atExpand
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Energy transfer mechanisms in Tb3+, Yb3+ codoped Y2O3 downconversion phosphor
Tb3+ and Yb3+ co-activated luminescent material that can cut one photon of around 483 nm into two NIR photons of around 1000 nm could be used as a downconversion luminescent convertor in front ofExpand
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Hydrothermal synthesis and characterization of two organically templated cadmium borophosphates with novel structures.
Two organically templated cadmium borophosphates, (C(4)H(16)N(3))[CdClB(2)P(3)O(12)(OH)] (1) and (C(2)H(10)N(2))[CdB(2)P(3)O(12)(OH)] (2), were synthesized hydrothermally in the presence ofExpand
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