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The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
We have identified a novel zinc finger-containing transcription factor, called Osterix (Osx), that is specifically expressed in all developing bones. In Osx null mice, no bone formation occurs. InExpand
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The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase*
The TAZ transcription co-activator promotes cell proliferation and epithelial-mesenchymal transition. TAZ is inhibited by the Hippo tumor suppressor pathway, which promotes TAZ cytoplasmicExpand
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Arabidopsis Argonaute10 Specifically Sequesters miR166/165 to Regulate Shoot Apical Meristem Development
The shoot apical meristem (SAM) comprises a group of undifferentiated cells that divide to maintain the plant meristem and also give rise to all shoot organs. SAM fate is specified by class IIIExpand
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The Human Epigenome Browser at Washington University
To the Editor: Advances in next-generation sequencing have reshaped the landscape of genomic and epigenomic research. Large consortia such as the Encyclopedia of DNA Elements, the Roadmap EpigenomicsExpand
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A heterozygous moth genome provides insights into herbivory and detoxification
How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemicallyExpand
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Adherence of Diarrheagenic Escherichia coli Strains to Epithelial Cells
An important early step in the colonization of the human gastrointestinal tract by bacteria is the adhesion of the organism to the host surface. Although adhesion is essential to maintain members ofExpand
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Conceptual and methodological issues relevant to cytokine and inflammatory marker measurements in clinical research
Purpose of reviewTo provide clinical investigators with an understanding of factors to consider when wishing to add cytokine and inflammatory marker measurements to their studies. RecentExpand
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Exploring long-range genome interactions using the WashU Epigenome Browser
To the Editor : Eukar yotic chromosomes are a highly organized three-dimensional entity folded through a tightly regulated process1,2 with important functions that include bringing distal regulatoryExpand
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Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix
The recent identification of the genes responsible for several human genetic diseases affecting bone homeostasis and the characterization of mouse models for these diseases indicated that canonicalExpand
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Flagellin of Enteropathogenic Escherichia coli Stimulates Interleukin-8 Production in T84 Cells
ABSTRACT The type III secretion system (TTSS) of enteropathogenic Escherichia coli (EPEC) has been associated with the ability of these bacteria to induce secretion of proinflammatory cytokines,Expand
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