Xin Yan-Fei

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N(G)-nitro-arginine (NNA) is known to exhibit stereoselective pharmacokinetics in which N(G)-nitro-d-arginine (d-NNA) has a faster clearance rate than N(G)-nitro-l-arginine (l-NNA) in anesthetized rats, and d-NNA undergoes unidirectional chiral inversion. It was postulated that chiral inversion of d-NNA was performed in a two-step pathway by d-amino acid(More)
N-nitro-arginine (NNA) is known to exhibit stereoselective pharmacokinetics in which D-NNA has a faster clearance rate than L-NNA in anesthetized rats, and D-NNA undergoes unidirectional chiral inversion. It was postulated that chiral inversion of D-NNA was performed in a two-step pathway by D-amino acid oxidase (DAAO) followed by an unidentified(More)
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