Xin W. Chen

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Intratumoural heterogeneity (ITH) is a major cause of cancer-associated lethality. Extensive genomic ITH has previously been reported in clear cell renal cell carcinoma (ccRCC). Here we address the question whether ITH increases with malignant progression and can hence be exploited as a prognostic marker. Unexpectedly, precision quantitative image analysis(More)
This article presents research on error detection and prediction algorithms in robotics. Errors, defined as either agent error or Co-net error, are analyzed and compared. Three new error detection and prediction algorithms (EDPAs) are then developed, and validated by detecting and predicting errors in typical pick and place motions of an Adept Cobra 800(More)
The purpose of this article is to review the key emerging innovations in laser and photonics systems as well as their design and integration, focusing on challenges and opportunities for solutions of societal challenges. Developments, their significance, and frontier challenges are explained in advanced manufacturing, biomedicine and healthcare, and(More)
OBJECTIVE New wild strains, which were endowed with an effective depilation as their abilities to produce keratinase, were isolated to develop the bio-deliplatory agent in the sulfur-free tanning. METHODS A polyphase screening method was used to obtain the high-yielding wild strains. In this method, the sewage sample was obtained from the specific(More)
a r t i c l e i n f o Logic needed for decision support to detect and resolve airport surface conflicts is defined in this article based on complex network theory. In this article, conflicts in airport surface operations are defined, along with a methodology to model and analyze airport surface constraints. The conflict detection and resolution logic take(More)