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People spend the majority of their time indoors, and human indoor activities are strongly correlated with the rooms they are in. Room localization, which identifies the room a person or mobile phone is in, provides a powerful tool for characterizing human indoor activities and helping address challenges in public health, productivity, building management,(More)
People spend approximately 70% of their time indoors. Understanding the indoor environments is therefore important for a wide range of emerging mobile personal and social applications. Knowledge of indoor floorplans is often required by these applications. However, indoor floorplans are either unavailable or obtaining them requires slow, tedious, and(More)
The use of past peak prices as reference points or judgmental anchors in valuing targets affects several aspects of merger and acquisition activity including offer prices, deal success, market reaction, and merger waves. Offer prices cluster at the target's recent peak prices, as well as 25% and 50% above recent peaks, even though these specific prices are(More)
Mitochondrial calcium has been postulated to regulate a wide range of processes from bioenergetics to cell death. Here, we characterize a mouse model that lacks expression of the recently discovered mitochondrial calcium uniporter (MCU). Mitochondria derived from MCU(-/-) mice have no apparent capacity to rapidly uptake calcium. Whereas basal metabolism(More)
In order to improve the oral bioavailability of ibuprofen, ibuprofen-loaded cubic nanoparticles were prepared as a delivery system for aqueous formulations. The cubic inner structure was verified by cryogenic transmission electron microscopy. With an encapsulation efficiency greater than 85%, the ibuprofen-loaded cubic nanoparticles had a narrow size(More)