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This paper reports a controlled study with statistical signi cance tests on ve text categorization methods: the Support Vector Machines (SVM), a k-Nearest Neighbor (kNN) classi er, a neural network (NNet) approach, the Linear Leastsquares Fit (LLSF) mapping and a Naive Bayes (NB) classier. We focus on the robustness of these methods in dealing with a skewed(More)
In this paper, we propose a novel document clustering method based on the non-negative factorization of the term-document matrix of the given document corpus. In the latent semantic space derived by the non-negative matrix factorization (NMF), each axis captures the base topic of a particular document cluster, and each document is represented as an additive(More)
In this paper, we propose two generic text summarization methods that create text summaries by ranking and extracting sentences from the original documents. The first method uses standard IR methods to rank sentence relevances, while the second method uses the latent semantic analysis technique to identify semantically important sentences, for summary(More)
Knowledge and investigation of therapeutic targets (responsible for drug efficacy) and the targeted drugs facilitate target and drug discovery and validation. Therapeutic Target Database (TTD, http://bidd.nus.edu.sg/group/ttd/ttd.asp) has been developed to provide comprehensive information about efficacy targets and the corresponding approved, clinical(More)
Purple acid phosphatases (PAPs) are members of the metallo-phosphoesterase family. They are characterized by the presence of seven conserved amino acid residues involved in coordinating the dimetal nuclear center in their reactive site. We compared the 29 PAPs predicted for Arabidopsis thaliana in their varieties of potential metal-ligating residues.(More)
This paper presents the design and implementation of a filter-based DoS defense system (StopIt) and a comparison study on the effectiveness of filters and capabilities. Central to the StopIt design is a novel closed-control, open-service architecture: any receiver can use StopIt to block the undesired traffic it receives, yet the design is robust to various(More)
Bread wheat (Triticum aestivum, AABBDD) is one of the most widely cultivated and consumed food crops in the world. However, the complex polyploid nature of its genome makes genetic and functional analyses extremely challenging. The A genome, as a basic genome of bread wheat and other polyploid wheats, for example, T. turgidum (AABB), T. timopheevii (AAGG)(More)
The goal of the Grid Application Development Software (GrADS) Project is to provide programming tools and an execution environment to ease program development for the Grid. This paper presents recent extensions to the GrADS software framework: a new approach to scheduling workflow computations, applied to a 3-D image reconstruction application; a simple(More)
Abiotic stresses cause serious crop losses. Knowledge on genes functioning in plant responses to adverse growth conditions is essential for developing stress tolerant crops. Here we report that transgenic expression of MYB15, encoding a R2R3 MYB transcription factor in Arabidopsis thaliana, conferred hypersensitivity to exogenous abscisic acid (ABA) and(More)
We present the design and evaluation of Passport, a system that allows source addresses to be validated within the network. Passport uses efficient, symmetric-key cryptography to place tokens on packets that allow each autonomous system (AS) along the network path to independently verify that a source address is valid. It leverages the routing system to(More)