Learn More
We present Dionysus, a system for fast, consistent network updates in software-defined networks. Dionysus encodes as a graph the consistency-related dependencies among updates at individual switches, and it then dynamically schedules these updates based on runtime differences in the update speeds of different switches. This dynamic scheduling is the key to(More)
Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which represent strong candidates for altitude adaptation, were(More)
Information networks are ubiquitous in many applications and analysis on such networks has attracted significant attention in the academic communities. One of the most important aspects of information network analysis is to measure similarity between nodes in a network. SimRank is a simple and influential measure of this kind, based on a solid theoretical(More)
Recently, there has been considerable interest in attribute based access control (ABAC) to overcome the limitations of the dominant access control models (i.e, discretionary-DAC, mandatory-MAC and role based-RBAC) while unifying their advantages. Although some proposals for ABAC have been published, and even implemented and standardized, there is no(More)
Cellular core networks suffer from inflexible and expensive equipment, as well as from complex control-plane protocols. To address these challenges, we present SoftCell, a scalable architecture that supports fine-grained policies for mobile devices in cellular core networks, using commodity switches and servers. SoftCell enables operators to realize(More)
As modern humans migrated out of Africa, they encountered many new environmental conditions, including greater temperature extremes, different pathogens and higher altitudes. These diverse environments are likely to have acted as agents of natural selection and to have led to local adaptations. One of the most celebrated examples in humans is the adaptation(More)
Here we integrate the de novo assembly of an Asian and an African genome with the NCBI reference human genome, as a step toward constructing the human pan-genome. We identified approximately 5 Mb of novel sequences not present in the reference genome in each of these assemblies. Most novel sequences are individual or population specific, as revealed by(More)
DNA methylation plays an important role in biological processes in human health and disease. Recent technological advances allow unbiased whole-genome DNA methylation (methylome) analysis to be carried out on human cells. Using whole-genome bisulfite sequencing at 24.7-fold coverage (12.3-fold per strand), we report a comprehensive (92.62%) methylome and(More)
We present CoVisor, a new kind of network hypervisor that enables, in a single network, the deployment of multiple control applications written in different programming languages and operating on different controller platforms. Unlike past hypervisors, which focused on slicing the network into disjoint parts for separate control by separate entities,(More)