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Gastric cancer is the second leading cause of cancer mortality in the world. Whether the oncogene, amplified on chromosome 3q26, SOX2, a master transcriptional regulator of stemness, operate to drive strong growth phenotype in gastric cancer were unknown. The gene expression changes of SOX2 in human gastric cancer tissues compared with non-cancerous tissues(More)
OBJECTIVE This prospective multicenter comparative study examined early and midterm results of medication and stent-graft therapies on chronic type B aortic dissection in China. METHODS The study consisted of 303 consecutive patients with chronic type B aortic dissection from four centers in China from January 2007 to December 2010 who were prospectively(More)
In this paper, we reported the realization of 2nd-order random lasing in a half-opened fiber cavity, which is formed by a FBG with central wavelength at the 1st-order Raman Stokes wavelength and a single-mode fiber (SMF) performing as a random distributed feedback mirror. Using this proposed method, the threshold of 1st-order (2nd-order) random lasing is(More)
Cardiomyocyte death (necrosis and apoptosis) plays a critical role in the progress of heart diseases. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L, has shown cardioprotective effects in vivo. However, whether salidroside has a protective effect against cardiomyocyte death is poorly understood. The present study was aimed to(More)
OBJECTIVE Misdiagnosis of primary aortoenteric fistula (PAEF) frequently occurs in clinical practice owing to the rarity of this condition. Herein we present the experience of diagnosis and management for PAEF. METHODS Eighteen patients with PAEF at 2 medical centers in China were reviewed. The clinical data, diagnostic procedures, treatment options, and(More)
Curcumin exerts an inhibitory effect on hepatic stellate cell (HSC) activation, a key step for liver fibrogenesis, and on liver fibrosis by up-regulation of peroxisome proliferator-activated receptor-γ (PPARγ) expression. PPARγ plays a crucial role in suppression of HSC activation. Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)(More)
Hepatic stellate cell (HSC) activation is a key cellular event in the development of liver fibrosis. Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been shown to function as a key transcription regulator linked to suppressing HSC activation. Compelling evidence indicates that leptin plays a unique role in the development of liver fibrosis.(More)
Renal artery aneurysm (RAA) is a rare event that may cause life-threatening rupture or renal function-threatening embolization. We report here a case of eccentric RAA involving the left upper pole renal artery and its three bifurcations, which was treated by stent plus coil embolization; the patient exhibited no renal insufficiency at 1-year follow-up. This(More)
BACKGROUND Pyrosequencing is a new method to detect single nucleotide polymorphisms (SNPs). Basal cell carcinoma (BCC) is one of the most common neoplasms in the world, and its incidence has been increasing worldwide in recent years. BCC is caused by an interplay between genetic and environment factors. METHODS Pyrosequencing and restrict fragment length(More)