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MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides
In a previous report (Young et al., Proc. Natl. Acad. Sci. U.S.A.2000,97, 5802–5806), we provided a proof-of-principle for fold recognition of proteins using a homobifunctional amine-specificExpand
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A Novel Regulator of Macrophage Activation: miR-223 in Obesity-Associated Adipose Tissue Inflammation
Background— Macrophage activation plays a crucial role in regulating adipose tissue inflammation and is a major contributor to the pathogenesis of obesity-associated cardiovascular diseases. OnExpand
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Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons
Sympathetic neurons from perinatal rat pups extend only a single axon when maintained in culture in the absence of glia and serum. Exposure to recombinant osteogenic protein-1 (OP-1) selectivelyExpand
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Palmitoleate Induces Hepatic Steatosis but Suppresses Liver Inflammatory Response in Mice
The interaction between fat deposition and inflammation during obesity contributes to the development of non-alcoholic fatty liver disease (NAFLD). The present study examined the effects ofExpand
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Fault reactivation and earthquakes with magnitudes of up to Mw4.7 induced by shale-gas hydraulic fracturing in Sichuan Basin, China
This paper presents a timely and detailed study of significant injection-induced seismicity recently observed in the Sichuan Basin, China, where shale-gas hydraulic fracturing has been initiated andExpand
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Glia Induce Dendritic Growth in Cultured Sympathetic Neurons by Modulating the Balance between Bone Morphogenetic Proteins (BMPs) and BMP Antagonists
Dendritic growth in cultured sympathetic neurons requires specific trophic interactions. Previous studies have demonstrated that either coculture with glia or exposure to recombinant boneExpand
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HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase*S⃞
Human T-cell leukemia virus type-1 is the causative agent for adult T-cell leukemia. Previous research has established that the viral oncoprotein Tax mediates the transformation process by impairingExpand
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Overexpression of peroxiredoxin 4 protects against high-dose streptozotocin-induced diabetes by suppressing oxidative stress and cytokines in transgenic mice.
Peroxiredoxin 4 (PRDX4) is one of a newly discovered family of antioxidative proteins. We generated human PRDX4 (hPRDX4) transgenic (Tg) mice, displaying a high level of hPRDX4 expression in theExpand
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Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses.
Systemic iron requirements are met predominantly through the recycling of iron from senescent erythrocytes by macrophages, a process in which the iron exporter ferroportin (Fpn1) is considered to beExpand
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Molecular and cellular mechanisms of neuroprotection by vascular endothelial growth factor
  • F. Sun, Xin Guo
  • Biology, Medicine
  • Journal of neuroscience research
  • 2005
The present view of the neuroprotective functions and mechanisms of action of vascular endothelial growth factor (VEGF) is based on studies of neuronal ischemic/hypoxic models in vivo and in vitro.Expand
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