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  • Xihui Xu, Yinan Hua, Sreejayan Nair, Yingmei Zhang, Jun Ren
  • Biology, Medicine
  • Journal of molecular cell biology
  • 2013 (First Publication: 1 February 2013)
  • Dear Editor, Accumulating studies have demonstrated that the autophagy–lysosome pathway, a major pathway governing protein and organelle degradation and recycling, is a house keeper in cardiomyocytesContinue Reading
  • Asli F Ceylan-isik, Machender Reddy Kandadi, +4 authors Sreejayan Nair
  • Medicine
  • Journal of molecular and cellular cardiology
  • 2013 (First Publication: 1 October 2013)
  • Apelin has been recognized as an adipokine that plays an important role in regulating energy metabolism and is credited with antiobesity and antidiabetic properties. This study was designed toContinue Reading
  • Xihui Xu, B. D. Pacheco, Lin Leng, Richard J Bucala, Jun Ren
  • Medicine, Biology
  • Cardiovascular research
  • 2013 (First Publication: 1 August 2013)
  • AIMS The cytokine macrophage migration inhibitory factor (MIF) protects the heart through AMPK activation. Autophagy, a conserved pathway for bulk degradation of intracellular proteins andContinue Reading
  • Nathan D. Roe, Xihui Xu, +4 authors Jun Ren
  • Medicine, Biology
  • Biochimica et biophysica acta
  • 2015 (First Publication: 1 February 2015)
  • Phosphatase and tensin homolog (PTEN) deleted from chromosome 10 has been implicated in the maintenance of cardiac homeostasis although the underlying mechanism(s) remains elusive. We generated aContinue Reading
  • Rui Guo, Xihui Xu, Sara A. Babcock, Yingmei Zhang, Jun Ren
  • Medicine
  • Journal of hepatology
  • 2015 (First Publication: 1 March 2015)
  • BACKGROUND & AIMS Mitochondrial aldehyde dehydrogenase (ALDH2) plays a critical role in the detoxification of the ethanol metabolite acetaldehyde. This study was designed to examine the impact ofContinue Reading
  • Qiurong Wang, Lifang Yang, Yinan Hua, Sreejayan Nair, Xihui Xu, Jun Ren
  • Medicine, Biology
  • Toxicological sciences : an official journal of…
  • 2014 (First Publication: 1 November 2014)
  • AIM Paraquat, a quaternary nitrogen herbicide, is a highly toxic prooxidant resulting in multi-organ failure including the heart although the underlying mechanism still remains elusive. This studyContinue Reading
  • Xihui Xu, Jun Ren
  • Medicine
  • International Journal of Obesity
  • 2015 (First Publication: 24 September 2014)
  • Background:Macrophage migration inhibitory factor (MIF) has a role in the development of obesity and diabetes. However, whether MIF has a role in fat diet-induced obesity and associated cardiacContinue Reading