Xie Xiaoping

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Accurate methods that test the eye irritation potential of chemicals, which do not involve the use of animals, are needed to meet new regulatory standards. We evaluated the applicability and predictive capacity of five in vitro tests for eye irritation: the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) assay; the Chorioallantoic Membrane-Trypan Blue(More)
In order to study the clinical significance and change of interleukin (IL)-1β and IL-10 concentration in intestinal mucosal tissues in various stage of ulcerative colitis (UC), IL-1β and IL10 levels were measured by enzyme linked immunosorbent assays (ELISA). Our results showed that IL-β level caused by spontaneous secretion in the intestinal mucous tissues(More)
To analyze the causes of failure in conventional treatment to refractory gastroesophageal reflux diseases (GERD) patients, 16 refractory GERD patients (group R) and 16 cases of GERD primarily diagnosed (group P) were studied. Endoscopy, pathologic examination and14C urea breath test were conducted in every patient. 24 h ambulatory pH and bilirubin(More)
The dysfunction in anxiety disease has been widely observed in clinics, but the underlying neural mechanism is not yet well understood. Function MRI data were collected conventionally 'imperfectly' with low frequency and short scans when participants were processing our experimental tasks. In order to find the nonlinear differences, we here propose the(More)
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