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GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner.
Recent advances indicate that cancer‑associated fibroblasts (CAFs) play a key role in cancer progression by contributing to invasion, metastasis and angiogenesis. Solid tumors often experience lowExpand
LINC00657 played oncogenic roles in esophageal squamous cell carcinoma by targeting miR-615-3p and JunB.
BACKGROUND The prognosis of esophageal squamous cell carcinoma (ESCC) is relatively poor due to the absence of efficient treatment. In this manuscript, we have investigated the specific roles andExpand
Lobaplatin promotes radiosensitivity, induces apoptosis, attenuates cancer stemness and inhibits proliferation through PI3K/AKT pathway in esophageal squamous cell carcinoma.
Radiotherapy is one of the common treatments for esophageal squamous cell carcinoma (ESCC). Yet, local recurrence led by radioresistance is still not solved. Lobaplatin (LBP) is known to haveExpand
Clinical effects of lianbai liquid in prevention and treatment of dermal injury caused by radiotherapy.
OBJECTIVE To observe the effect of Lianbai liquid in prevention and treatment of acute radiation dermal injury. METHOD From May 2000 to December 2005, 126 cancer patients were randomly divided intoExpand
PTENP1 inhibits the growth of esophageal squamous cell carcinoma by regulating SOCS6 expression and correlates with disease prognosis
PTEN pseudogene (PTENP1) has a tumor suppressive role in multiple cancers. However, its involvement in esophageal squamous cell carcinoma (ESCC) remains largely unknown. In this study, we set out toExpand
Lung cancer therapy using doxorubicin and curcumin combination: Targeted prodrug based, pH sensitive nanomedicine.
  • Y. Hong, S. Che, +5 authors Hailin Ma
  • Chemistry, Medicine
  • Biomedicine & pharmacotherapy = Biomedecine…
  • 1 April 2019
Lung cancer is the leading cause of cancer death worldwide. To overcome the toxic side effects and multidrug resistance (MDR) during doxorubicin (DOX) chemotherapy, a urokinase plasminogen activatorExpand
Epigenetic interventions increase the radiation sensitivity of cancer cells.
Epigenetic changes including DNA methylation, histone modifications, chromatin remodeling and microRNAs play critical roles in tumorigenesis and tumor development. Reversal of epigenetic changesExpand
HDAC as a therapeutic target for treatment of endometrial cancers.
Accumulating evidence suggested that epigenetic changes such as promoter-specific DNA hypermethylation and histone deacetylation cause tumor suppressor gene silencing and contribute to malignantExpand
A20 enhances the radiosensitivity of hepatocellular carcinoma cells to 60Co-γ ionizing radiation
The radioresistance of hepatocellular carcinoma (HCC) cells is a critical obstacle for effectively applying radiotherapy (RT) in HCC treatment. NF-κB, an important transcription factor, can influenceExpand
Lysophosphatidic Acid Inhibits Apoptosis Induced by Cisplatin in Cervical Cancer Cells
Cervical cancer is the second most common cause of cancer death in women worldwide. Lysophosphatidic acid (LPA) level has been found significantly increased in the serum of patients with ovarian,Expand