Learn More
We investigate the channel assignment problem in a cluster-based multi-channel cognitive radio sensor network in this paper. Due to the inherent power and resource constraints of sensor networks, energy efficiency is the primary concern for network design. An R-coefficient is developed to estimate the predicted residual energy using sensor information(More)
Modern General-Purpose computation on Graphics Processing Units (GPGPUs) explore parallelism in applications by building massively parallel architecture and apply multithreading technology to hide the instruction and memory latencies. Such architectures become increasingly popular for parallel applications using CUDA/OpenCL programming languages. In this(More)
Cyclin-dependent kinases (CDKs) are essential in the control of cell cycle progression. Inhibition of CDKs represents a new approach for pharmacological intervention in the treatment of a variety of proliferative diseases, especially cancer. Based on the crystal structure of CDK2 in complex with an imidazole indolinone compound 1 (SU9516), lead optimization(More)
Here we report that bis(7)-tacrine, a novel acetylcholinesterase inhibitor, exerts neuroprotective effects by inhibition of nitric oxide synthase. In cortical neurons at 12 days in vitro, bis(7)-tacrine concentration-dependently reduced cell death induced by glutamate, beta-amyloid and L-arginine, but not by nitric sodium nitroprusside.(More)
The excessive activation of the N-methyl-D-aspartate receptor (NMDAR)/nitric oxide (NO) pathway has been proposed to be involved in the neuropathology of various neurodegenerative disorders. In this study, NO was found to mediate glutamate-induced excitotoxicity in primary cultured neurons. Compared with the NO synthase (NOS) inhibitor,(More)
Curcumin, a traditional medicine, exhibits anticarcinogenic properties in various cell lines and animals. As a phenolic compound, curcumin is light-sensitive and photoactived curcumin exhibits a greater anticancer effect compared with curcumin alone. However, the mechanisms by which curcumin inhibits tumor cell growth in human nasopharyngeal carcinoma (NPC)(More)
Perspective distortion often appears in the image documents which were token by digital camera. This phenomenon will lead to recognition errors or failures. Therefore, a new correction algorithm is proposed in this paper for perspective distortion images of Chinese documents. The algorithm makes use of Chinese document image's horizontal characteristics of(More)
This paper proposed a modified vertical-Bell Labs layered space-time (V-BLAST) system, where different delay offsets are intentionally applied to the spatially multiplexed data streams in order to improve bit error rate (BER) performance. The proposed system can use only one receive antenna to recover the transmitted information by zero forcing (ZF)(More)
A new series of compounds, 5-substituted 2-amino-4-chloro-8-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7,8-dihydropteridin-6(5H)-ones, have been designed and identified as potent and selective inhibitors of Hsp90. These compounds demonstrated nanomolar potency toward both Hsp90-regulated Her2 degradation and the growth of a panel of human tumor cell lines(More)