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The molecular subsets of glioma behave in biologically distinct ways. The present study detected isocitrate dehydrogenase (IDH) 1 and IDH2 mutations in glioma to analyze whether IDH-mutated gliomas are situated in certain preferential areas and to investigate their correlation with magnetic resonance imaging (MRI) characteristics. A series of 193 patients… (More)
Large scale syntheses of uniform metal nanoparticles with hollow porous structure have attracted much attention owning to their high surface area, abundant active sites and relatively efficient catalytic activity. Herein, we report a general method to synthesize hollow porous Pd nanospheres (Pd HPNSs) by templating sacrificial SiO2 nanoparticles with the… (More)
Research in the field of WSD has been conducted in computational linguistics as a specific task for many years. Language and context features have been shown to be very helpful for the task of word sense disambiguation. In this paper, we investigate the effectiveness of the graph-based ranking method on features from limited language data of word sense… (More)
OBJECTIVE To explore the clinical efficacies of bevacizumab (BEV) for high-grade glioma (HGG) in Chinese patients and evaluate its profiles of adverse events and usage safety. METHODS A total of 15 HGG cases, including glioblastoma multiform (GBM) (n = 12) and anaplastic astrocytoma (AA) (n = 3), were selected to receive the treatments of BEV (10 mg/kg,… (More)
Fluorogenic hydroxylamine reagents were used for detecting 5-fC through a labeling pathway. Chemical synthesis, HPLC, denaturing PAGE, and DNA MS were applied to testify that the probe reacted with 5-fC with oligodeoxynucleotide selectivity to achieve 5-fC detection conveniently and quantificationally with the method of fluorescence. The feasibility of… (More)
Fluorescent nucleosides (dU(bmz)) with desirable fluorescence quantum yield (Φ) are synthesized from almost non-fluorescent 5-fdU and o-phenylenediamine derivatives. The fluorescence of these nucleosides is quite sensitive to pH and organic solvents. 4-Methoxybenzene-1,2-diamine was used for the detection of 5-fdU among natural nucleosides.