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— We present a new initial ranging method for OFDMA systems such as IEEE 802.16-2004. First, a new orthogonal ranging signal design is proposed by which an efficient, low-complexity multiuser ranging signal detection is developed. Based on the ranging signal detector results, power estimation for the detected ranging subscriber stations is performed. Then,(More)
Broadband wireless access technology is developed very fast in recent years. The IEEE 802.16 and 802.11a are two broadband wireless access system standards for metropolitan and local areas respectively. The IEEE 802.11a works in the license-exempt (LE) band, and the IEEE 802.16 is designed such that it can operate in the same LE spectrum too. Although the(More)
—We address joint estimation of frequency offsets and channel responses in OFDMA uplink. A cyclically equal-spaced, equal-energy interleaved pilot preamble is proposed by which two iterative estimators are developed. In the first estimator, we develop a modified SAGE (space alternating generalized expectation-maximization) method by incorporating multiuser(More)
In this paper, we obtain a global exact controllability result for a class of multidi-mensional semilinear hyperbolic equations with a superlinear nonlinearity and variable coefficients. For this purpose, we establish an observability estimate for the linear hyperbolic equation with an unbounded potential, in which the crucial observability constant is(More)
miR-210 is upregulated in a HIF-1α-dependent way in several types of cancers. In addition, upregulated miR-210 promotes cancer proliferation, via its anti-apoptotic effects. It is blind to the regulation of miR-210 under hypoxia conditions for ovarian cancer cells and to the effect of miR-210 on ovarian cancer growth. In the present study, we determined the(More)
Doxorubicin (DOX) is a highly effective anti-neoplastic agent; however, its cumulative dosing schedules are clinically limited by the development of cardiotoxicity. Previous studies have attributed the cause of DOX-mediated cardiotoxicity to mitochondrial iron accumulation and the ensuing reactive oxygen species (ROS) formation. The present study(More)
Hepatitis B virus X protein (HBx) is recognized as an oncogene in hepatocellular carcinoma (HCC). HBx regulates microRNA expression, including down-regulating miR-338-3p in LO2 cells. Here, we investigated miR-338-3p function in HBx-mediated hepatocarcinogenesis. In 23 HBV-infected HCC clinical patient tumor and adjacent non-tumor control tissues, 17 and 19(More)
PURPOSE Previous research has proposed that the hypomethylating agent decitabine can sensitize ovarian cancer cells to chemical agents. In this open-label, phase I/II clinical study, we analyzed the toxicity and efficacy of low dose decitabine combined with taxol and platinum chemotherapy in treatment of refractory and recurrent ovarian cancer. METHODS(More)
By constructing a genomic library, an endoglucanase gene (cel9P) was cloned from Paenibacillus sp. BME-14 which was isolated from the sea. It had an open-reading frame of 1,629 bp, encoding a peptide of 542-amino acid residue with a calculated molecular mass of 60 kDa. The enzyme showed the highest amino acid identity of 52% with other known endoglucanases(More)
BACKGROUND Astrocyte elevated gene-1(AEG-1) plays an important role in the development and progression of certain types of human cancers. However, the expression dynamics of AEG-1 in cervical cancer and its clinical/prognostic significance are unclear. METHOD In present study, the methods of tissue microarrays (TMA) and immunohistochemistry (IHC) were(More)