• Publications
  • Influence
[Application of network pharmacology and high through-put technology on active compounds screening from traditional Chinese medicine].
OBJECTIVE To solve the difficult in the active compounds screening from traditional Chinese medicines (TCM). METHOD According to preliminary lab results and related literature, systematic analysisExpand
  • 8
  • 1
Ellagic acid improves endogenous neural stem cells proliferation and neurorestoration through Wnt/β‐catenin signaling in vivo and in vitro
Scope: The aim of this study is to research the effects of the polyphenol ellagic acid (EA) on brain cells and to explore its mechanism of action, and to evaluate whether EA can be safely utilized byExpand
  • 13
Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture.
In order to efficiently screen and isolate β-tubulin inhibitors, β-tubulin was immobilized on core-shell PMMA/CS (poly(methyl methacrylate)/Chitosan) nanoparticles to produce a new type ofExpand
  • 6
Dual roles of ynoates: desymmetrization of dicarboxylic acids using trialkylamines as alkyl equivalents
A novel method has been developed for the desymmetrization of aromatic dicarboxylic acids by employing an esterification reaction/conjugate addition of a carboxyl group to ynoates, which can triggerExpand
  • 4
  • PDF
Organocatalytic synthesis of 5-hydroxyisoxazolidine catalyzed by camphor sulfonyl hydrazines through aza-Michael addition/cyclization.
A series of chiral 5-hydroxy isoxazolidines has been successfully synthesized through camphor sulfonyl hydrazine-catalyzed asymmetric aza-Michael addition reaction between N,O-protected hydroxyaminesExpand
Pharmacokinetics, Tissue Distribution, and Druggability Prediction of the Natural Anticancer Active Compound Cytisine N-Isoflavones Combined with Computer Simulation.
Cytisine N-methylene-(5,7-dihydroxy-4'-methoxy)-isoflavone (CNF2) is a new compound isolated from the Chinese herbal medicine Sophora alopecuroides. Preliminary pharmacodynamic studies demonstratedExpand
[Chemical constituents contained in Macropanax rosthornii].
OBJECTIVE To study active constituents of Macropanax rosthornii in treating rheumatoid arthritis. METHOD Silica gel column chromatography, preparative HPLC and modern spectrum techniques wereExpand
  • 1