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  • Xiaoyan Zhou, Ming Tan, +7 authors Dihua Yu
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 2004 (First Publication: 15 October 2004)
  • The Akt/mammalian target of rapamycin (mTOR)/4E-BP1 pathway is considered to be a central regulator of protein synthesis, involving the regulation of cell proliferation, differentiation, andContinue Reading
  • Jing Lu, H Guo, +13 authors Dihua Yu
  • Biology, Medicine
  • Cancer cell
  • 2009 (First Publication: 1 September 2009)
  • ErbB2, a metastasis-promoting oncoprotein, is overexpressed in approximately 25% of invasive/metastatic breast cancers, but in 50%-60% of noninvasive ductal carcinomas in situ (DCIS). It has beenContinue Reading
  • Kristine S. Klos, Xiaoyan Zhou, +4 authors Dihua Yu
  • Medicine
  • Cancer
  • 2003 (First Publication: 1 October 2003)
  • BACKGROUND Trastuzumab (Herceptin; Genentech, South San Francisco, CA) is a humanized anti-ErbB-2 monoclonal antibody that has demonstrated antitumor function, especially in combination with otherContinue Reading
  • Lei Dong, Wanrun Lin, +9 authors Xiang Du
  • Medicine, Biology
  • Cancer epidemiology, biomarkers & prevention : a…
  • 2016 (First Publication: 1 July 2016)
  • BACKGROUND Long noncoding RNA (lncRNA) and mRNAs are long RNAs (≥200 nucleotides) compared with miRNAs. In blood, long RNAs may be protected by serum extracellular vesicles, such as apoptotic bodiesContinue Reading