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  • Xiaoyan Shen, Kaifeng Xu, Qingyuan Fan, Gustavo Pacheco-Rodríguez, Joel Moss, Martha Vaughan
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2006 (First Published: 21 February 2006)
  • ADP-ribosylation factors (ARFs) are critical in vesicular trafficking. Brefeldin A-inhibited guanine nucleotide-exchange protein (BIG)1 and BIG2 activate ARFs by accelerating replacement of bound GDPContinue Reading
  • Aminul Islam, Xiaoyan Shen, Toyoko Hiroi, Joel Moss, Martha Vaughan, Stewart J Levine
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2007 (First Published: 30 March 2007)
  • The type I, 55-kDa tumor necrosis factor receptor (TNFR1) is released from cells to the extracellular space where it can bind and modulate TNF bioactivity. Extracellular TNFR1 release occurs by twoContinue Reading
  • Xiaoyan Shen, Víctor Meza-Carmen, Ermanno Puxeddu, Guanghui Wang, Joel Moss, Martha Vaughan
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2008 (First Published: 2 December 2008)
  • Brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 activates human ADP-ribosylation factor (ARF) 1 and 3 by accelerating the replacement of ARF-bound GDP with GTP to initiateContinue Reading
  • Kai-Feng Xu, Xiaoyan Shen, Hewang Li, Gustavo Pacheco-Rodríguez, Joel Moss, Martha Vaughan
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Published: 22 February 2005)
  • Guanine nucleotide-exchange proteins activate ADP-ribosylation factors by accelerating the replacement of bound GDP with GTP. Mammalian brefeldin A-inhibited guanine nucleotide-exchange proteins,Continue Reading
  • Xiaoyan Shen, Chun-Chun Li, +4 authors Martha Vaughan
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2012 (First Published: 4 September 2012)
  • Brefeldin A-inhibited guanine nucleotide-exchange protein (BIG)2 activates ADP-ribosylation factors, ∼20-kDa GTPase proteins critical for continuity of intracellular vesicular trafficking byContinue Reading
  • Xiaoyan Shen, Myoung-Soon S. Hong, Joel Moss, Martha Vaughan
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2007 (First Published: 23 January 2007)
  • Glycosylation of beta1 integrin (beta1) in the Golgi complex has been related to its function in multiple cell processes, e.g., invasiveness, matrix adhesion, and migration. Brefeldin A-inhibitedContinue Reading