Xiaoxiang Zhao

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The present experiments were undertaken to characterize the hearing loss associated with 1,1,2-trichloroethylene (TCE) exposure. Adult male Long-Evans (LE) rats were exposed to TCE via inhalation (whole body) for 6 h/day for 5 days. The concentration-effect function (0-4000 ppm) was determined 3 weeks post-exposure. Animals were tested for auditory(More)
The mechanism of neurotoxicity of 3,3'-iminodipropionitrile (IDPN) has been widely debated, with either the parent compound or putative metabolites implicated in various studies. The N-hydroxylated form of IDPN (HO-IDPN) has been reported to cause the excitation with choreiform and circling (ECC) syndrome in rats at doses approximately one-eighth of that(More)
To study the toxic effects of phthalate esters on the aquatic creatures, carps were exposed to dibutyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP) of six different concentrations for 96 h-LC50 measurements. It shows that the 96 h-LC50 is 16.30 and 37.95 mg L(-1), thus the safe concentration (1/10LC(50)) is 1.63 mg L(-1). The activities of xanthine(More)
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