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BACKGROUND Human leukocyte antigen DP (HLA-DP) locus has been reported to be associated with hepatitis B virus (HBV) infection in populations of Japan and Thailand. We aimed to examine whether the association can be replicated in Han Chinese populations. METHODOLOGY/PRINCIPAL FINDINGS Two HLA-DP variants rs2395309 and rs9277535 (the most strongly(More)
Pulmonary Langerhans cell histiocytosis (PLCH) has been postulated to be a smoking-related non-neoplastic condition, distinct from extrapulmonary LCH, which is generally regarded as a clonal, neoplastic process. Recent genomic studies demonstrated BRAF V600E mutation in 38% to 57% of extrapulmonary LCH cases by polymerase chain reaction. We evaluated the(More)
OBJECTIVES To evaluate the clinical and laboratory features of patients with lupus nephritis (LN) in the presence and absence of anti-glomerular basement membrane antibodies (anti-GBM) and to establish whether the characteristics of the disease correlate with anti-GBM. METHODS We performed a retrospective study of 157 hospitalised patients with systemic(More)
Donor-acceptor conjugated polymers PBDT-DTBT and PBDT-DTNT, based on 2,1,3-benzothiadiazole (BT) and naphtho[1,2-c:5,6-c]bis[1,2,5]thiadiazole (NT), have been designed and synthesized for polymer solar cells. NT contains two fused 1,2,5-thiadiazole rings that lower the band gap, enhance the interchain packing, and improve the charge mobility of the(More)
OBJECTIVE Aspiration can cause a variety of pulmonary syndromes, some of which are not well recognized. The objective of this study was to assess the demographic, clinical, radiological, and histopathological correlates of diffuse aspiration bronchiolitis (DAB), a bronchiolocentric disorder caused by recurrent aspiration. METHODS This was a retrospective(More)
A series of novel conjugated copolymers based on naphtho[1,2-c:5,6-c]bis(2-octyl-[1,2,3]triazole) (TZNT) are synthesized. These copolymers exhibit medium bandgaps of ≈1.9 eV. One of them demonstrates a high performance of up to 6.10% power conversion efficiency in a bulk-heterojunction (BHJ) solar-cell device. The performance can be further enhanced to(More)
BACKGROUND Aspiration occurs commonly, at times clinically occult, and is recognized to cause a widening spectrum of lung disorders. Presentation of aspiration as a lung mass has not been described. METHODS Among cases of aspiration-related pulmonary diseases diagnosed at Mayo Clinic (Rochester, Minn) from 2007 to 2013, 3 patients were identified to have(More)