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Sterile alpha motif and HD-domain containing protein 1 (SAMHD1) is a newly identified intracellular antiviral factor. By depleting the dNTPs pool of host cells to a low level that cannot support the efficient synthesis of viral cDNA, it restricts replication of some retroviruses. As a DNA virus, Hepatitis B virus (HBV) experiences a process of reverse(More)
Modern operating systems avoid duplication of code and data when they are mapped by multiple processes by sharing physical memory through mechanisms like copy-on-write. Nonetheless, a separate copy of the virtual address translation structures, such as page tables, are still maintained for each process, even if they are identical. This duplication can lead(More)
Sterile α motif and HD domain-containing protein 1 (SAMHD1) is a novel intrinsic restriction factor that inhibits the replication of certain retroviruses and DNA viruses through its deoxynucleoside triphosphate triphosphohydrolase activity. A previous study by our group showed that SAMHD1 restrained hepatitis B virus replication and interferon (IFN)‑α(More)
—We analyze the instruction access patterns of Android applications. Although Android applications are ordinarily written in Java, we find that native-code shared libraries play a large role in their instruction footprint. Specifically, averaging over a wide range of applications, we find that 60% of the instruction pages accessed belong to native-code(More)
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