Xiaoquan Xu

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BACKGROUND This study aimed to evaluate the feasibility of intraarterial (IA) delivery and in vivo MR imaging of superparamagnetic iron oxide (SPIO)-labeled mesenchymal stem cells (MSCs) in a canine stroke model. METHODOLOGY MSCs harvested from beagles' bone marrow were labeled with home-synthesized SPIO. Adult beagle dogs (n = 12) were subjected to left(More)
It is estimated that lacunar infarcts account for 25% of all ischemic strokes, but its exact etiology is still on debating. The existing controversies include whether the embolisms can indeed cause lacunar stroke in humans or animal models. We hypothesized that lacunar infarction can be induced by the proximal middle cerebral artery (MCA) segmental(More)
OBJECTIVE To quantitatively evaluate nerve roots by measuring fractional anisotropy (FA) values in healthy volunteers and sciatica patients, visualize nerve roots by tractography, and compare the diagnostic efficacy between conventional magnetic resonance imaging (MRI) and DTI. MATERIALS AND METHODS Seventy-five sciatica patients and thirty-six healthy(More)
AIMS This retrospective study was carried out to compare the outcomes between elderly (≥70 years of age) and nonelderly patients (<70 years of age) with advanced hepatocellular carcinoma (HCC) who received sorafenib combined with transarterial chemoembolization (TACE). METHODS 88 patients with a confirmed diagnosis of advanced HCC were enrolled in this(More)
OBJECTIVE To investigate the effect of age, gender and laterality on the intravoxel incoherent motion (IVIM) MR imaging measurements of parotid glands in healthy participants at 3.0-T MRI. METHODS A total of 108 healthy participants were prospectively recruited. IVIM MRI scan was performed using a 3.0-T MR scanner, and corresponding parameters (perfusion(More)
In acute stroke magnetic resonance imaging, many attempts have been made to identify the onset time of ischemic events using the simply quantitative judgment of relative signal intensity (rSI) from various MR images. However, no uniform opinion has been achieved broadly till now. The controversy might derive from the potential patients' selection bias of(More)
The aim of our study is to compare the image quality of readout-segmented echo-planar imaging (rs-EPI) and that of standard single-shot EPI (ss-EPI) in orbital 3 T diffusion-weighted (DW) magnetic resonance (MR) imaging in healthy subjects. Forty-two volunteers underwent two sets of orbital DW imaging scan at a 3 T MR unit, and image quality was assessed(More)
The aim of the present study was to determine the efficacy of quantitative measurements of the lacrimal gland based on 3‑T magnetic resonance (MR) imaging in the diagnosis and staging of Graves' ophthalmopathy (GO). The study retrospectively enrolled 33 patients with GO (the GO group) and 24 healthy volunteers [the healthy control (HC) group] with orbit MR(More)