Xiaoqin J. Guo

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Specific human leukocyte antigen (HLA) DQB1 alleles confer strong susceptibility to systemic sclerosis (SSc). However, the frequencies of specific DQB1 alleles and their associations with SSc vary according to ethnicity and clinical features of SSc. The aim of this study was to profile DQB1 alleles in a Chinese population and to identify specific DQB1(More)
Proper characterization of waste is important to reduce the costs of disposal. The requirement for short data collection time often means putting the detector as close to the waste container as possible. Nondestructive assay of gamma ray emitting nuclear waste requires modeling because preparing a standard to match the physical and radiological properties(More)
A high performance frontal analysis(HPFA) method was developed to determine the unbound concentration of drugs in drug-human serum albumin (HSA) mixture under binding equilibrium. The sample was injected directly onto an internal-surface reversed-phase silica column (ISRP). The mobile phase was 67 mmol/L phosphate buffer (pH 7.4, I = 0.17 mol/L). When a(More)
Uniform design method was employed to optimize the mobile phase of HPLC in order to determine simultaneously three principal components, theophylline, amobarbital and methylephedrine hydrochloride, in Chuanjing tablet, a compound preparation for asthma and cough. The stationary phase was ODS and the optimal mobile phase composition was V (0.015 mol/L(More)
A simple and rapid HPLC-UV method has been developed for determination of levofloxacin in human plasma. Chromatographic separation was performed on a Kromasil C18 column with the mobile phase consisting of acetonitrile, water, phosphoric acid and triethylamine (14:86:0.6:0.3, v/v/v/v) and flow rate was 1.0 mL/min. The method used ultraviolet detection set(More)
Applying electrical impulse stimuli at the Jing point (St. 45) and then tapping on the skin surface along the vertical lines crossing the channel of the stomach, the line of latent propagated sensation along channel (LPSC) was determined in 51 patients at the acupuncture clinic. Of the cases examined, 98 percent were found to have positive LPSC lines which(More)
Environmental factors are believed to play an important role in the pathogenesis of systemic sclerosis (SSc). Silica exposure has been implicated as potentially hazardous in epidemiological studies of SSc. It can activate fibroblasts to express profibrotic genes at certain conditions. The aim of this study is to examine whether the fibroblasts of SSc(More)
Early rehabilitative therapy is important for patients with hypertensive cerebral hemorrhage to improve long-term function of the extremities. Vascular endothelial growth factor (VEGF) is closely associated with the pathogenesis of hypertension. To identify the markers contributing to the genetic susceptibility to hypertensive cerebellar hemorrhage (HCH)(More)
Nondestructive assay of gamma-ray emitting nuclear waste requires modeling because it is not practical to prepare a standard that matches the physical and nuclear properties of every waste item. The use of a high-purity germanium (HPGe) detector simplifies the spectral analysis process. Many models use simplified efficiency determinations and attenuation(More)
OBJECTIVE To differentiate the effects of inhibition of specific small interfering RNA (siRNA) of SPARC (secreted protein, acidic and rich in cysteine) and siRNA of connective tissue growth factor (CTGF) in cultured human fibroblasts, and to identify potential interrelationships between SPARC and CTGF. METHODS Fibroblasts from skin biopsy specimens of 2(More)