Learn More
Osteoclast differentiation is a complex and finely regulated physiological process that involves a variety of signaling pathways and factors. Recent studies suggested that the Ser9 phosphorylation of Glycogen synthase kinase-3β (GSK3β) is required for the osteoclast differentiation. However, the precise underlying mechanism remains unclear. We have(More)
The essence characteristics of software trustworthiness are software execution effect and behavior can be anticipated, which is an important index of software quality. Under the open and dynamic environments, some uncertainty factors cause the behavior of software to be uncontrolled, uncertainty and unpredictable. Behavior-aware networked software(More)
Phosphatidylserine (PS) and docosahexaenoic acid-phosphatidylserine (DHA-PS) have significant nutritional and biological functions, which are extensively used in functional food industries. Phospholipase D (PLD)-mediated transphosphatidylation of phosphatidylcholine (PC) or DHA-PC with l-serine, is an effective method for PS and DHA-PS preparation. However,(More)
The human immunodeficiency virus (HIV) protein negative factor (Nef) is important for AIDS pathogenesis. An anti-Nef single-domain antibody (sdAb19) derived from camelids has been previously generated and shown to effectively block the physiological functions of Nef in vitro and in vivo in nef-transgenic mice. However, sdAb19 must be ectopically expressed(More)
c-FLIP (cellular FLICE-inhibitory protein) is the pivotal regulator of TRAIL resistance in cancer cells, It is a short-lived protein degraded through the ubiquitin/proteasome pathway. The discovery of factors and mechanisms regulating its protein stability is important for the comprehension of TRAIL resistance by tumor cells. In this study, we show that,(More)
With the development of Internet and Web service technology, Web service composition has been an effective way to construct software applications; service selection is the crucial element in the composition process. However, the existing selection methods mostly generate static plans since they neglect the inherent stochastic and dynamic nature of Web(More)
Under the open environments, it is very difficult to guarantee the trustworthiness of interacting business process using traditional software engineering methods, at the same time, for dealing with the influence of external factors, some proposed business process mining methods are only effective 1-bounded business process, and some behavior dependent(More)
The Service composition has been a popular research presently. Service Composition by manual cannot meet the expectations in reality, but the wholly intellectualized automatic service composition is a very complicated process. So, many applications and research about service composition are oriented to semi-automatic service composition, for obtaining(More)