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Genome-wide identification, characterization, and expression analyses of the HAK/KUP/KT potassium transporter gene family reveals their involvement in K+ deficient and abiotic stress responses in
High-affinity K+ (HAK)/K+ uptake (KUP)/K+ transporters (KT) play crucial roles in the regulation of cellular K+ levels. However, little is known about these genes in the Rosaceae family. In thisExpand
Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma
TLDR
DNA methylation induced silencing of TET2 and TET3 are responsible for the EMT-like process and the metastasis of melanoma, and data suggest an epigenetic circuitry that mediates the E MT activated by TGF-β. Expand
Transcriptome Analysis of Differentially Expressed Genes Induced by Low and High Potassium Levels Provides Insight into Fruit Sugar Metabolism of Pear
TLDR
The gene expression patterns of leaves and fruit in response to different K levels during the middle and late stages of fruit development as well as the molecular mechanism of improvement of fruit sugar levels by K were revealed and provided a scientific basis for improving fruit quality with supplemental K fertilizers. Expand
The change in microstructure of petioles and peduncles and transporter gene expression by potassium influences the distribution of nutrients and sugars in pear leaves and fruit.
TLDR
The concentration of sorbitol, sucrose, and total sugar in leaves and fruit at maturity significantly increased in response to the supply of K, which may promote the transport of nutrients and sugar from sources to sinks and increase the accumulation of sugar in the fruit. Expand
Reticulocalbin 3 Deficiency in Alveolar Epithelium Exacerbated Bleomycin‐induced Pulmonary Fibrosis
TLDR
It is suggested that bleomycin‐induced upregulation of Rcn3 in AECIIs appears to contribute to AECII survival and wound healing, and shed additional light on the mechanism of idiopathic pulmonary fibrosis. Expand
The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation and puncture (CLP) in mice
TLDR
The remodeling of HDL composition in sepsis, which predisposes lung to ARDS via inducing ECs dysfunction, is depicted and the importance of circulating HDL in regulating alveolar homeostasis is demonstrated. Expand
A high-density BAC physical map covering the entire MHC region of addax antelope genome
TLDR
The successful construction of a high-quality physical map for the addax MHC region using BACs and comparative mapping provides compelling evidence that the MHC organizations in all of the ruminant species are relatively conserved. Expand
Functional, Ultrastructural, and Transcriptomic Changes in Rat Diaphragms with Different Durations of Cigarette Smoke Exposure
TLDR
Observations suggested a transition of diaphragm muscle from initial compensatory to decompensatory changes in function, structure, and gene expression during the development of COPD. Expand
Human Papillomavirus 16 oncoprotein E7 retards mitotic progression by blocking Mps1-MAP4 signaling cascade
TLDR
A molecular mechanism by which HPV16E7 perturbs host mitotic progression by interfering Mps1-MAP4 signaling cascade is revealed, which results in an extended infection window and may facilitate the persistent HPV16 infection. Expand
Different value of HDL-C in predicting outcome of ARDS secondary to bacterial and viral pneumonia: A retrospective observational study.
TLDR
High density lipoprotein-cholesterol levels in ARDS patients secondary to bacterial and viral pneumonia might be a valuable marker to assess the 28-d mortality for bacterial AR DS patients rather than viral ARDS Patients. Expand
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