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PURPOSE To determine whether automatic and manual measurements of hippocampal volume differences on MRI between normal aging, cognitive impairment (CI), and Alzheimer's disease (AD) yield similar results. MATERIALS AND METHODS Reliability was determined for an automatic and a manual method on nine volunteers (22-83 years old) who underwent MRI twice in 1(More)
From mid-July to the end of August 2005, a total of 215 cases of human Streptococcus suis infections, 66 of which were laboratory confirmed, were reported in Sichuan, China. All infections occurred in backyard farmers who were directly exposed to infection during the slaughtering process of pigs that had died of unknown causes or been killed for food(More)
  • Feng Geng, Xiaoping Zhu
  • 2007
A new adaptive fuzzy control algorithm which combines sliding mode controller and a proportional-integral controller into a single adaptive fuzzy sliding mode controller (AFSMC) is proposed for a nonlinear system - an inverted pendulum system. The AFSMC can tackle the control problem of unknown nonlinear systems and systems with modeling uncertainties and(More)
Normal aging is associated with diminished brain perfusion measured as cerebral blood flow (CBF), but previously it is difficult to accurately measure various aspects of perfusion hemodynamics including: bolus arrival times and delays through small arterioles, expressed as arterial-arteriole transit time. To study hemodynamics in greater detail, volumetric(More)
The goal was to assess regional patterns of metabolite abnormalities in mild cognitive impairment (MCI) and Alzheimer disease (AD) patients using proton magnetic resonance spectroscopy imaging at 1.5 Tesla. Fourteen MCI, 17 AD, and 16 healthy control (HC) subjects were studied. MCI was associated with higher myo-inositol (mIn) concentration in right(More)
An outbreak of Streptococcus suis serotype 2 emerged in the summer of 2005 in Sichuan Province, and sporadic infections occurred in 4 additional provinces of China. In total, 99 S. suis strains were isolated and analyzed in this study: 88 isolates from human patients and 11 from diseased pigs. We defined 98 of 99 isolates as pulse type I by using(More)
An extended model for extracting measures of brain perfusion from pulsed arterial spin labeling (ASL) data while considering transit effects and restricted permeability of capillaries to blood water is proposed. We divided the time course of the signal difference between control and labeled images into four phases with respect to the arrival time of labeled(More)
Model-based techniques have the potential to reduce the artifacts and improve resolution in magnetic resonance spectroscopic imaging, without sacrificing the signal-to-noise ratio. However, the current approaches have a few drawbacks that limit their performance in practical applications. Specifically, the classical schemes use less flexible image models(More)
MR spectroscopic (MRS) images from a large volume of brain can be obtained using a 3D echo-planar spectroscopic imaging (3D-EPSI) sequence. However, routine applications of 3D-EPSI are still limited by a long scan time. In this communication, a new approach termed "spectral phase-corrected generalized autocalibrating partially parallel acquisitions"(More)
OBJECTIVE During June 2 - 8, 2009, 11 cases of the novel influenza A (H1N1) occurred in Sichuan Province, China. We investigated this outbreak to identify the source of infection, mode of transmission and risk factors for infection. METHODS The primary case, a U.S. citizen, developed disease on June 2. From June 3 to 5, she joined Tour Group A for a trip(More)