Xiaoping Shen

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Endothelial dysfunction is a key triggering event in atherosclerosis. Following the entry of lipoproteins into the vessel wall, their rapid modification results in the generation of advanced glycation endproduct epitopes and subsequent infiltration of inflammatory cells. These inflammatory cells release receptor for advanced glycation endproduct (RAGE)(More)
0142-0615/$ see front matter 2009 Elsevier Ltd. A doi:10.1016/j.ijepes.2009.03.017 * Corresponding author. Tel.: +1 201 216 8057; fax E-mail addresses: hhe@stevens.edu, hhbhust@gma An Energy Difference of Multiresolution Analysis (EDMRA) method for power quality (PQ) disturbances analysis has been proposed in this paper. At each wavelet decomposition level,(More)
OBJECTIVE There are several pathways that mediate the aberrant metabolism of glucose and that might induce greater vascular damage in the setting of diabetes. The polyol pathway mediated by aldose reductase (AR) has been postulated to be one such pathway. However, it has been reported that AR reduces toxic lipid aldehydes and, under some circumstances,(More)
In this paper, we construct infinite-band filterbanks for perfect reconstruction (PR) using Hermite polynomials and Hermite functions. The analysis filters are linear combinations of derivative operators based on these polynomials-the so-called chromatic derivative filters. Together with the synthesis filterbanks, they give PR for a large class of signals(More)
This paper presents the research of using bootstrap methods for time-series prediction. Unlike the traditional single model (neural network, support vector machine, or any other types of learning algorithms) based time-series prediction, we propose to use bootstrap methods to construct multiple learning models, and then use a combination function to combine(More)
Diabetes exacerbates cardiovascular disease, at least in part through suppression of macrophage cholesterol efflux and levels of the cholesterol transporters ATP binding cassette transporter A1 (ABCA1) and ABCG1. The receptor for advanced glycation end products (RAGE) is highly expressed in human and murine diabetic atherosclerotic plaques, particularly in(More)
Highly stable graphene aqueous dispersions were achieved by chemical reduction of graphene oxide with an environmentally friendly reagent of hexamethylenetetramine (HMTA). By this method, chemical reduction as well as dispersion of graphene can be carried out in one step without the need of organic stabilizers or pH control. The as-synthesized products were(More)
Whether the variations in the cholesterol 24S-hydroxylase (CYP46A1) gene would raise Alzheimer's risk is still undetermined. A previous meta-analysis about the association between AD susceptibility and CYP46A1 intron-2T/C (rs754203) has led to inconsistent conclusions. To assess the relationship between the CYP46A1 rs754203 polymorphism and AD risk more(More)
The continuous prolate spheroidal wave functions (Slepian functions) were found to be useful for analog signal processing several decades ago. But the digital revolution left then1 in the dust since they did not seem naturally adapted to discrete analysis. Yet they have many desirable, even unique, properties that originally made them fascinating and could(More)
OBJECTIVE Subjects with diabetes mellitus are at high risk for developing atherosclerosis through a variety of mechanisms. Because the metabolism of glucose results in production of activators of protein kinase C (PKC)β, it was logical to investigate the role of PKCβ in modulation of atherosclerosis in diabetes mellitus. APPROACH AND RESULTS ApoE(-/-) and(More)