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The sea cucumber genome provides insights into morphological evolution and visceral regeneration
A complete genome sequence of an economically important sea cucumber, A. japonicus, generated using Illumina and PacBio platforms is presented to provide a useful framework for future research into biological processes and evolution in deuterostomes, including remarkable regenerative abilities that could have medical applications. Expand
Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress
Investigation of alterations in miRNA expression in the sea cucumber under different levels of dissolved oxygen suggested that these miRNAs are important in redox, transport, transcription, and hydrolysis under hypoxia stress. Expand
RNA Editing, ADAR1, and the Innate Immune Response
Critical findings from ADAR1 mechanistic studies focusing on its regulatory function in innate immune responses are reviewed and some of the important unanswered questions in the field are identified. Expand
Comparative Phospho- and Acetyl Proteomics Analysis of Posttranslational Modifications Regulating Intestine Regeneration in Sea Cucumbers
Sea cucumbers exposed to stressful circumstances eviscerate most internal organs, and then regenerate them rapidly under favorable environments. Reversible protein phosphorylation and acetylation areExpand
Development strategies for the sea cucumber industry in China
The sea cucumber, Apostichopus japonicus, is an important marine aquaculture species in China. After nearly thirty years of development, the production of A. japonicus has become commerciallyExpand
Characteristics of nitrogen forms in the southern Huanghai Sea surface sediments
The distributions of different forms of nitrogen in the surface sediments of the southern Huanghai Sea are different and affected by various factors. The contents of IEF-N, SOEF-N and TN graduallyExpand
Understanding regulation of microRNAs on intestine regeneration in the sea cucumber Apostichopus japonicus using high-throughput sequencing.
High-throughput sequencing applied to investigate alterations of miRNA expression in regenerative intestine compared to normal intestine suggested that these miRNAs play important roles in specific cellular events (cell proliferation, migration, and apoptosis), metabolic regulation, and energy redistribution. Expand
Extracellular matrix remodeling and matrix metalloproteinases (ajMMP-2 like and ajMMP-16 like) characterization during intestine regeneration of sea cucumber Apostichopus japonicus.
A fibronectin-dominate temporary matrix is created in intestine regeneration, and it might provide structural integrity for matrix and promote cell movement, which provides new evidence of ECM and MMPs involvement in sea cucumber regeneration. Expand
Metabolic responses to intestine regeneration in sea cucumbers Apostichopus japonicus.
Three important genes were differentially expressed to regulate the levels of betaine and N,N-dimethylglycine during intestine regeneration in sea cucumbers, providing an important basis for studying regenerative mechanisms and developing regenerative matrixes. Expand
Identification and expression characterization of WntA during intestinal regeneration in the sea cucumber Apostichopus japonicus.
  • Xiaoni Li, Lina Sun, +4 authors D. Huo
  • Biology, Medicine
  • Comparative biochemistry and physiology. Part B…
  • 1 August 2017
Results suggested that WntA might participate in intestinal regeneration and may be connected with cell proliferation, apoptosis in different intestinal layers. Expand