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  • Paul Haluska, Joan M. Carboni, +7 authors Charles Erlichman
  • Medicine, Biology
  • Molecular Cancer Therapeutics
  • 2008 (First Publication: 1 September 2008)
  • We have reported previously the activity of the insulin-like growth factor-I (IGF-IR)/insulin receptor (InsR) inhibitor, BMS-554417, in breast and ovarian cancer cell lines. Further studies indicatedContinue Reading
  • Sean Dowdy, Shujuan Jiang, +4 authors Shi-wen Jiang
  • Medicine, Biology
  • Molecular Cancer Therapeutics
  • 2006 (First Publication: 1 November 2006)
  • The use of histone deacetylase (HDAC) inhibitors has shown promise for a variety of malignancies. In this investigation, we define the activity of this class of inhibitors in combination withContinue Reading
  • Mariam M Alhilli, Marc A. Becker, +15 authors Paul Haluska
  • Medicine
  • Gynecologic oncology
  • 2016 (First Publication: 1 November 2016)
  • OBJECTIVE Poly(ADP-ribose) polymerase (PARP) inhibitors have yielded encouraging responses in high-grade serous ovarian carcinomas (HGSOCs), but the optimal treatment setting remains unknown. WeContinue Reading