Xiaoming Wang

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This paper examines graph-theoretic properties of existing peer-to-peer architectures and proposes a new infrastructure based on optimal diameter de Bruijn graphs. Since generalized de Bruijn graphs possess very short average routing distances and high resilience to node failure, they are well suited for structured peer-to-peer networks. Using the example(More)
This paper presents a new approach to structural topology optimization. We represent the structural boundary by a level set model that is embedded in a scalar function of a higher dimension. Such level set models are flexible in handling complex topological changes and are concise in describing the boundary shape of the structure. Furthermore, a wellfounded(More)
This article shares our experience in designing a Web crawler that can download billions of pages using a single-server implementation and models its performance. We first show that current crawling algorithms cannot effectively cope with the sheer volume of URLs generated in large crawls, highly branching spam, legitimate multimillion-page blog sites, and(More)
New linear response formulas for unperturbed chaotic (stochastic) complex dynamical systems with time periodic coefficients are developed here. Such time periodic systems arise naturally in climate change studies due to the seasonal cycle. These response formulas are developed through the mathematical interplay between statistical solutions for the(More)
Previous analytical results on the resilience of unstructured P2P systems have not explicitly modeled heterogeneity of user churn (i.e., difference in online behavior) or the impact of in-degree on system resilience. To overcome these limitations, we introduce a generic model of heterogeneous user churn, derive the distribution of the various metrics(More)
Off-patent drugs with previously unrecognized anticancer activity could be rapidly repurposed for this new indication. To identify such compounds, we conducted 2 independent cell-based chemical screens and identified the antimicrobial ciclopirox olamine (CPX) in both screens. CPX decreased cell growth and viability of malignant leukemia, myeloma, and solid(More)
Fusarium ear rot is a prevalent disease in maize, reducing grain yields and quality. Resistance breeding is an efficient way to minimize losses caused by the disease. In this study, 187 lines from a RIL population along with the resistant (87-1) and susceptible (Zong 3) parents were planted in Zhengzhou and Beijing with three replications in years 2004 and(More)
Follicular dendritic cells (FDCs) retain and display opsonized antigens in primary follicles and germinal centers (GCs). However, their roles beyond antigen presentation have been incompletely defined. In this study, we tested the impact of selective FDC ablation on short-term follicle and GC function. Within 2 d of FDC ablation, primary follicles lost(More)
Thinopyrum ponticum and Th. intermedium provide superior resistance against various diseases in wheat (Ttricum aestivum). Because of their readily crossing with wheat, many genes for disease resistance have been introduced from the wheatgrasses into wheat. Genes for resistance to leaf rust, stem rust, powdery mildew, Barley yellow dwarf virus, Wheat streak(More)
A heterogeneous object is referred to as a solid object made of different constituent materials. The object is of a finite collection of regions of a set of prescribed material classes of continuously varying material properties. These properties have a discontinuous change across the interface of the material regions. In this paper, we propose a level-set(More)