Xiaoming Wang

Learn More
This paper examines graph-theoretic properties of existing peer-to-peer architectures and proposes a new infrastructure based on optimal diameter de Bruijn graphs. Since generalized de Bruijn graphs possess very short average routing distances and high resilience to node failure, they are well suited for structured peer-to-peer networks. Using the example(More)
This paper presents a new approach to structural topology optimization. We represent the structural boundary by a level set model that is embedded in a scalar function of a higher dimension. Such level set models are flexible in handling complex topological changes and are concise in describing the boundary shape of the structure. Furthermore, a wellfounded(More)
SHANK3 is a synaptic scaffolding protein enriched in the postsynaptic density (PSD) of excitatory synapses. Small microdeletions and point mutations in SHANK3 have been identified in a small subgroup of individuals with autism spectrum disorder (ASD) and intellectual disability. SHANK3 also plays a key role in the chromosome 22q13.3 microdeletion syndrome(More)
This article shares our experience in designing a Web crawler that can download billions of pages using a single-server implementation and models its performance. We first show that current crawling algorithms cannot effectively cope with the sheer volume of URLs generated in large crawls, highly branching spam, legitimate multimillion-page blog sites, and(More)
New linear response formulas for unperturbed chaotic (stochastic) complex dynamical systems with time periodic coefficients are developed here. Such time periodic systems arise naturally in climate change studies due to the seasonal cycle. These response formulas are developed through the mathematical interplay between statistical solutions for the(More)
Yellow rust (stripe rust), caused by Puccinia striiformis Westend f. sp. tritici, is one of the most devastating diseases of wheat throughout the world. Wheat-Haynaldia villosa 6AL.6VS translocation lines R43, R55, R64 and R77, derived from the cross of three species, carry resistance to both yellow rust and powdery mildew. An F2 population was established(More)
Previous analytical results on the resilience of unstructured P2P systems have not explicitly modeled heterogeneity of user churn (i.e., difference in online behavior) or the impact of in-degree on system resilience. To overcome these limitations, we introduce a generic model of heterogeneous user churn, derive the distribution of the various metrics(More)
Fusarium ear rot is a prevalent disease in maize, reducing grain yields and quality. Resistance breeding is an efficient way to minimize losses caused by the disease. In this study, 187 lines from a RIL population along with the resistant (87-1) and susceptible (Zong 3) parents were planted in Zhengzhou and Beijing with three replications in years 2004 and(More)
Off-patent drugs with previously unrecognized anticancer activity could be rapidly repurposed for this new indication. To identify such compounds, we conducted 2 independent cell-based chemical screens and identified the antimicrobial ciclopirox olamine (CPX) in both screens. CPX decreased cell growth and viability of malignant leukemia, myeloma, and solid(More)