Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis
- Xiaoming Gong, Xiaoli Tang, Z. Mao
- Biology, ChemistryNeuron
- 10 April 2003
Role of macular xanthophylls in prevention of common neovascular retinopathies: retinopathy of prematurity and diabetic retinopathy.
- Xiaoming Gong, L. Rubin
- MedicineArchives of Biochemistry and Biophysics
- 15 April 2015
Cyclin-Dependent Kinase 5 Mediates Neurotoxin-Induced Degradation of the Transcription Factor Myocyte Enhancer Factor 2
- Xiaoli Tang, Xuemin Wang, Z. Mao
- BiologyJournal of Neuroscience
- 11 May 2005
The convergence of Cdk5 phosphorylation-dependent caspase-mediated degradation of nuclear survival factors exemplified by MEF2 may represent a general process applicable to the regulation of other survival factors under diverse neurotoxic conditions.
Stromal cell derived factor‐1 acutely promotes neural progenitor cell proliferation in vitro by a mechanism involving the ERK1/2 and PI‐3K signal pathways *
- Xiaoming Gong, Xiang-ping He, Lei Qi, H. Zuo, Zuo-ping Xie
- BiologyCell Biology International
- 1 May 2006
Carotenoid Lutein Selectively Inhibits Breast Cancer Cell Growth and Potentiates the Effect of Chemotherapeutic Agents through ROS-Mediated Mechanisms
- Xiaoming Gong, Joshua R Smith, Haley M Swanson, L. Rubin
- BiologyMolecules
- 1 April 2018
Dietary lutein supplementation may be a promising alternative and/or adjunct therapeutic candidate against breast cancer through increased cell type-specific ROS generation and alternation of several signaling pathways.
Mitochondrial β-Carotene 9′,10′ Oxygenase Modulates Prostate Cancer Growth via NF-κB Inhibition: A Lycopene-Independent Function
- Xiaoming Gong, Raju Marisiddaiah, S. Zaripheh, D. Wiener, L. Rubin
- BiologyMolecular Cancer Research
- 12 July 2016
BCO2-mediated inhibition of NF-κB signaling implies BCO2 status is important in prostate cancer progression, and previously unanticipated functions of B CO2 are described that are independent of its enzymatic role in lycopene metabolism.
Cooperation between MEF2 and PPARγ in human intestinal β,β-carotene 15,15'-monooxygenase gene expression
- Xiaoming Gong, S. Tsai, B. Yan, L. Rubin
- BiologyBMC Molecular Biology
- 21 February 2006
The findings suggest that the interaction between MEF2 and PPAR factors may provide a molecular basis for interspecies differences in the transcriptional regulation of the BCMO1 gene.
Effects of insulin-like growth factor 1 on synaptic excitability in cultured rat hippocampal neurons
- C. Xing, Yanling Yin, Rui Chang, Xiaoming Gong, Xiang-ping He, Zuo-ping Xie
- BiologyExperimental Neurology
- 1 May 2007
Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2.
- Xuemin Wang, Xiaoli Tang, Xiaoming Gong, E. Albanis, S. Friedman, Z. Mao
- Biology, MedicineGastroenterology
- 1 October 2004
The studies provide the first evidence for the presence of MEF2 in the liver and show thatMEF2 regulates multiple aspects of HSC activation, showing a novel role of MEf2 as a key nuclear mediator that may participate in the pathologic process of liver fibrogenesis in vivo.
Invivo insulin deficiency as a potential etiology for demyelinating disease.
- Xiaoming Gong, Zuo-ping Xie, H. Zuo
- Biology, MedicineMedical Hypotheses
- 1 September 2008
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