Xiaolong Tang

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OBJECTIVES Hemorrhage is considered to be the primary sign of Dengue hemorrhagic fever and Dengue shock syndrome. In the present study we focused on the mechanism in the pro- and anti-coagulation after Dengue virus infection. METHODS The effects of Dengue virus on the expression and secretion of tissue factor, tissue factor inhibitor, thrombomodulin,(More)
Adhesion G-protein-coupled receptors (GPCR), which contain adhesion domains in their extracellular region, have been found to play important roles in cell adhesion, motility, embryonic development, and immune response. Because most adhesion molecules with adhesion domains have vital roles in cancer metastasis, we speculated that adhesion GPCRs are(More)
Production compilers' optimizers typically operate at low abstraction levels, transformation rules enacting on operations on built-in types only. Transformations at higher levels of abstraction, on operations of types defined in libraries or by the user, are typically not supported. Such high-level optimizations could, however, yield greater benefits than(More)
Phrynocephalus vlangalii is a species of lizard endemic in China, which lives on Qinghai-Tibet Plateau ranging from 2000 to 4600 m above sea level. In this study, P. vlangalii were collected from low altitude (2750 m) and high altitude (4564 m). The lizards from low altitude were acclimatized in simulated hypoxic chamber (equivalent to 4600 m) for 7, 15,(More)
Mucinous gastric carcinoma (MGC) is a rare kind of malignancy with unclear prognosis. This study aims to assess the clinicopathological features and prognosis of MGC. We retrospectively analyzed a consecutive series of 244 MGC patients who underwent radical gastrectomy with D2 lymphadenectomy, and compared the data with 260 gastric signet ring cell(More)
The efficient delivery of therapeutic drugs into interested cells is a critical challenge to broad application of nonviral vector systems. In this research, emtansine (DM1)-loaded star-shaped folate-core polylactide-d-α-tocopheryl polyethylene glycol 1000 succinate (FA-PLA-TPGS-DM1) copolymer which demonstrated superior anticancer activity in vitro/vivo in(More)
Fatal fungal infections in central nervous system (CNS) can occur through hematogenous spread or direct extension. At present, hydrophobic amphotericin B (AMB) is the most effective antifungal drug in clinical trials. However, AMB is hydrophobic and therefore penetrates poorly into the CNS, and therapeutic levels of AMB are hard to achieve. The transferrin(More)
Fungal infections are an important cause of morbidity and mortality in immunocompromised patients. Amphotericin B (AMB), with broad-spectrum antifungal activity, has long been recognized as a powerful fungicidal drug, but its clinical toxicities mainly nephrotoxicity and poor solubility limit its wide application in clinical practice. The fungal metabolism(More)
OBJECTIVE To identify clinicopathological characters and risk factors of malignant pancreatic solid pseudopapillary neoplasm (SPN). METHODS All patients with complete clinicopathological records who underwent surgery for SPN between 2000 and 2010 were retrospective reviewed. Furthermore, we reviewed and classified the histopathology slides of all patients(More)
The effects of hypoxia on behavioral thermoregulation, rate of heating and cooling, hysteresis of heart rate, and standard metabolic rate (SMR) were investigated in Phrynocephalus przewalskii, a small size toad headed lizard. Preferred temperature (T(b)) descended when lizards were exposed to severe hypoxia (8% O(2) and 6% O(2)) for 22 h, and lizards were(More)