Xiaolong Qi

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Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive assessment of physiologic stenosis significance and an indispensable tool for decision-making in coronary revascularization. Robust studies have shown that FFR is more effective in accurately identifying which lesions should be stented, and revascularization guided by FFR(More)
Lymphangiogenesis plays a significant role in metastasis and recurrence of gastric cancer. There is no report yet focusing on the modulation of VEGF pathway and lymphangiogenesis of gastric cancer by targeting Akt/mTOR pathway. This study aims to demonstrate the relationship between Akt/mTOR pathway and VEGF-C/-D in gastric cancer. We collected surgically(More)
The translocator protein (18 kDa) (TSPO) is a five transmembrane domain protein in mitochondria, abundantly expressed in a variety of organs and tissues. TSPO contributes to a wide range of biological processes, including cholesterol transportation, mitochondrial membrane potential and respiratory chain regulation, apoptosis, and oxidative stress. Recent(More)
1 Coronary stenosis with lumen diameter reduction greater than 50% is recognized as coronary artery disease (CAD) [1-4]. Fractional flow reserve (FFR) is an epicardial lesion-specific parameter to determine the functional coronary stenosis, which is determined by pressure difference and resistance [5-8]. Previous studies have demonstrated that FFR guided(More)
BACKGROUND & OBJECTIVES Discrepancies exist in the reported prevalence of portal vein thrombosis (PVT), and its clinical characteristics and sites of occurrence need to be elucidated. The risk factors for PVT are also poorly understood. This single centre study was undertaken to determine the clinical characteristics, sites of occurrence, and risk factors(More)
BACKGROUND Some studies have found that the NAD(P)H quinone oxidoreductase 1 (NQO1) SNP609 is associated with an increased risk for several malignancies. Numerous epidemiological studies have evaluated the association between the NQO1 C609T polymorphism and the risk of prostate cancer. However, the results of these studies have been conflicting. The aim(More)
Primary synovial sarcoma of the prostate is an uncommon malignant tumor. There are few cases reported in the English medical literature to date. Here, we present a case of 22-year-old man with primary synovial sarcoma of the prostate metastatic to the liver and lung. To our knowledge, only six reports of synovial sarcoma involving the prostate have been(More)
A 72-year-old male was diagnosed incidentally with a 7-cm renal tumor in the right moiety of a horseshoe kidney during a routine physical examination, and was treated with laparoscopic radical heminephrectomy. The surgical time was 153 min and the estimated blood loss was 150 ml. The patient was discharged on post-operative day eight with no complications.(More)
  • Jun Huang, Yongzhao Zhao, Yong Xu, Yanjie Zhu, Jiale Huang, Yanna Liu +5 others
  • 2016
BACKGROUND & AIMS Platinum-based drugs are the most significant chemotherapy for advanced gastric cancer. The study aims to compare the efficacy and safety of oxaliplatin-based therapy versus cisplatin-based therapy in patients with advanced gastric cancer. MATERIALS AND METHODS An adequate literature search in EMBASE, Cochrane Central Register of(More)
BACKGROUND Cyclin D1 (CCND1) is critical in the transition of the cell cycle from the G1 to S phases, and unbalanced cell cycle regulation is a hallmark of carcinogenesis. Numerous epidemiological studies have evaluated the association between the CCND1 A870G polymorphism and the risk of prostate cancer (PCa). However, these studies have yielded conflicting(More)