Xiaolin Xue

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Neuronal oscillations are fundamental to hippocampal function. It has been shown that GABAergic interneurons make an important contribution to hippocampal oscillations, but the underlying mechanism is not well understood. Here, using whole-cell recording in the complete hippocampal formation isolated from rats at postnatal days 14–18, we showed that GABAA(More)
Alzheimer's disease (AD) is the most common form of dementia and causes impairments of memory, cognition and behavior. Remarkably, most AD patients exhibit personality changes that often precede other early clinical manifestations. Conditional presenilin1 (PS1) and presenilin2 (PS2) double knockout (DKO) mice have age-related forebrain atrophy, tau(More)
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