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The human immunodeficiency virus (HIV)-1 protein Vif has a central role in the neutralization of host innate defences by hijacking cellular proteasomal degradation pathways to subvert the antiviral activity of host restriction factors; however, the underlying mechanism by which Vif achieves this remains unclear. Here we report a crystal structure of the(More)
The CRISPR-Cas systems, as exemplified by CRISPR-Cas9, are RNA-guided adaptive immune systems used by bacteria and archaea to defend against viral infection. The CRISPR-Cpf1 system, a new class 2 CRISPR-Cas system, mediates robust DNA interference in human cells. Although functionally conserved, Cpf1 and Cas9 differ in many aspects including their guide(More)
Silver nanowires have been successfully synthesized via a simple solvothermal method by adding sodium sulfide (Na(2)S) into the solution. The Ag(2)S colloids produced in the initial stage help reduce the concentration of free Ag(+) ions in the initial formation of silver seeds and subsequently release Ag(+) ions to the solution. Otherwise, there is no(More)
Here we report a facile, surfactant-free and template-free synthesis process of highly uniform dendritic silver nanostructures with high catalytic activity for the reduction of p-nitrophenol. By controlling the concentration of AgNO(3) aqueous solution and the reaction time, various shapes of silver nanodendrites (SNDs) could be obtained easily. The effects(More)
Silver nanostructures have been synthesized via a microwave-assisted polyol method by adding sodium sulfide (Na(2)S) into the solution. An interesting morphology evolution can be observed by adjusting the concentration of Na(2)S and the heating power. It is found that the ideal concentration of Na(2)S is 31.25-500 microM for the fast reduction of Ag(+) at(More)
In this paper, a facile process was developed for anchoring of silver nanoparticles on graphitic carbon nitride sheets (Ag/g-C3N4) with high catalytic activity for reduction of 4-nitrophenol. The morphology and structure of the as-prepared Ag/g-C3N4 composite were investigated by FESEM, TEM, XRD and XPS. The reaction mechanism and the reduction kinetics of(More)
Silver nanoparticles (Ag NPs) were prepared via a wet-chemical method in the presence of poly(vinyl pyrrolidone) (PVP) without other reducing agents at room temperature. The influence of the addition of water on the preparation of Ag NPs was investigated. It was found that water addition has a significant influence on the reduction reaction, resulting in(More)
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