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PURPOSE To investigate the spatiotemporal properties of the cortical responses elicited by intraorbital optic nerve (ON) stimulation with penetrating electrodes as means of designing optimal stimulation strategies for an ON visual prosthesis. METHODS The ON of rabbits was exposed by orbital surgery for electrical stimulation. Craniotomy was performed to(More)
BACKGROUND Smoking is a risk factor for many human diseases. DNA methylation has been related to smoking, but genome-wide methylation data for smoking in Chinese populations is limited. OBJECTIVES We aimed to investigate epigenome-wide methylation in relation to smoking in a Chinese population. METHODS We measured the methylation levels at > 485,000 CpG(More)
Data warehousing technology has made a huge impact in the world of business; it helps to turn data into information that helps analysts to make strategic decisions. Currently most data warehouse approaches employ static refresh mechanisms. But for various business requirements this is not an appropriate solution. Some critical data need to be refreshed in(More)
BACKGROUND Epidemiological studies have suggested an association between external estimates of exposure to metals in air particles and altered heart rate variability (HRV). However, studies on the association between internal assessments of metals exposure and HRV are limited. OBJECTIVES The purpose of this study was to examine the potential association(More)
Visual prosthesis is a potential way to restore partial vision for the patients with degenerative retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Optic nerve stimulation with penetrating microelectrode array has been suggested as a possible method for visual prosthesis. The purpose of this study was to(More)
A low carbon, high efficiency and high quality power supply scheme for Distributed Generation (DG) in a micro-grid is presented. A three-phase, four-leg DG grid-interfacing converter based on the improved structure of a Unified Power Quality Conditioner (UPQC, including a series converter and a parallel converter) is adopted, and improved indirect and(More)
Plant communities on Mount Segrila on the Tibetan Plateau show distinct changes at different altitudes, but little information is available on belowground communities of arbuscular mycorrhizal fungi (AMF). Root samples of two co-occurring species, Pennisetum centrasiaticum and Kobresia sp., growing in open grasslands at eight altitudes (3,446–4,556 m) were(More)
This paper is concerned with stability analysis of biological networks modeled as discrete and finite dynamical systems. We show how to use algebraic methods based on quantifier elimination, real solution classification and discriminant varieties to detect steady states and to analyze their stability and bifurcations for discrete dynamical systems. For(More)