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Prior evidence shows that acupuncture improves symptoms in both Parkinson's disease (PD) patients and animal models. We examined the effects of high-frequency (100 Hz) electroacupuncture (EA) on behavior in a rat PD model induced by medial forebrain bundle (MFB) transection. Neurotransmitters levels in the striatum were measured using in vivo microdialysis(More)
OBJECTIVE The intent of this study was to evaluate the clinical outcome and risk factors affecting mortality of the continuous ambulatory peritoneal dialysis (CAPD) patients in a single peritoneal dialysis (PD) center over a period of 10 years. PATIENTS AND METHODS We retrospectively analyzed patients on PD from June 2001 to June 2011. The clinical and(More)
Parkinson's disease (PD) is an aging-associated neurodegenerative disorder with progressive pathology involving the loss of midbrain dopaminergic neurons. Neurotrophic factors are promising for PD gene therapy; they are integrally involved in the development of the nigrostriatal system. Cerebral dopamine neurotrophic factor (CDNF) was recently discovered to(More)
The complex pathogenesis of Alzheimer's disease (AD) involves multiple contributing factors, including amyloid β (Aβ) peptide accumulation, inflammation and oxidative stress. Effective therapeutic strategies for AD are still urgently needed. Triptolide is the major active compound extracted from Tripterygium wilfordii Hook.f., a traditional Chinese(More)
Jian Wu, Ji Zang, Brian Larade, Hong Guo, X. G. Gong, and Feng Liu,* Center for Advanced Study, Tsinghua University, Beijing 100084, People’s Republic of China Department of Materials Science and Engineering, University of Utah, Salt Lake City, Utah 84112, USA Department of Physics, McGill University, Montreal, Canada PQ H3A 2T8 Department of Physics, Fudan(More)
Microglia are key players for the inflammatory responses in the central nervous system. Suppression of microglial activation and the resulting production of proinflammatory molecules are considered a promising strategy to alleviate the progression of neurodegenerative disorders. Triptolide was demonstrated as a potent anti-inflammatory compound both in(More)
TBBPA-induced genes were identified using suppression subtractive hybridization (SSH) from Chlamys farreri. A total of 203 and 44 clones from SSH forward and reverse library were respectively obtained including cellular process, immune system process, response to stimulus, metabolic process and signaling etc. Differential gene expressions were compared(More)
L. Huang,1 Feng Liu,2,3 and X. G. Gong1,4,3 1Surface Physics Laboratory and Department of Physics, Fudan University, Shanghai 200433, People’s Republic of China 2Department of Materials Science and Engineering, University of Utah, Salt Lake City, Utah 84112, USA 3Interdisciplinary Center for Theoretical Studies, Chinese Academy of Sciences, Beijing 100080,(More)
The acupuncture or electroacupuncture (EA) shows the therapeutic effect on various neurodegenerative diseases. This effect was thought to be partially achieved by its ability to alleviate existing neuroinflammation and glial dysfunction. In this study, we systematically investigated the effect of EA on abnormal neurochemical changes and motor symptoms in a(More)
We show, by first-principles calculations, that the effect of external strain on surface diffusion is inherently correlated with the intrinsic surface stress induced by the adatom along its diffusion pathways. We demonstrate a simple generic method for a priori predicting quantitatively how an external strain will change surface diffusion on any given(More)