Xiaoli Du

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The excision repair cross-complementation group 1 (ERCC1) plays an essential role in DNA repair and has been linked to resistance to platinum-based anticancer drugs among advanced non-small cell lung cancer (NSCLC) patients. We systematically evaluate whether ERCC1 Asn118Asn and C8092A genetic variants are associated with treatment response of platinum(More)
BACKGROUND Many studies have been done to find out the molecular mechanism of systemic acquired resistance (SAR) in plants in the past several decades. Numbers of researches have been carried out in the model plants such as arabidopsis, tobacco, rice and so on, however, with little work done in woody plants especially in fruit trees such as apple.(More)
OBJECTIVES To investigate the potential of nevirapine 200 mg once-daily regimen and evaluate the influence of patient characteristics on nevirapine concentrations. METHODS This was a prospective, multicentre cohort study with 532 HIV-infected patients receiving nevirapine as a part of their initial antiretroviral therapy. Plasma samples were collected at(More)
Cramer JP. Post-treatment haemolysis in severe imported malaria after intravenous artesunate: case report of three patients with hyperparasitaemia. Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium. Cramer JP. Artesunate versus quinine in the treatment of severe imported malaria: comparative analysis(More)
Diva is a member of the Bcl2 family but its function in apoptosis remains largely unclear because of its specific expression found within limited adult tissues. Previous overexpression studies done on various cell lines yielded conflicting conclusions pertaining to its apoptotic function. Here, we discovered the expression of endogenous Diva in PC12(More)
—Coordination among users is an indispensable part in wireless networks for efficient medium access. Alone with the rapid increase of transmission rate, however, coordination time becomes insufferable. We present AFD, namely asymmetric full duplex, to achieve high coordination efficiency at nearly zero overhead. In AFD, channel contention is performed(More)
Cronobacter spp. (Enterobacter sakazakii) is an important pathogen contaminating powdered infant formula (PIF). To describe the genotypic diversity of Cronobacter isolated in China, we identified the isolates using fusA allele sequencing, and subtyped all of the isolates using pulsed-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST), and(More)
25 unprecedented insights into many macromolecular machines in fundamental life processes 1,2. By 26 directly imaging the biological samples frozen in buffer solutions, cryo-EM circumvents the 27 need to obtain well-ordered crystals, a major bottleneck in traditional crystallographic methods 28 for high resolution structure determination. Single particle(More)
High performance liquid chromatography was coupled with UV detection for simultaneous quantification of lopinavir (LPV) and ritonavir (RTV) in human plasma. This assay was sensitive, accurate and simple, and only used 200 μL of plasma sample. Samples were liquid-liquid extracted, and diazepam was used as an internal standard. The chromatographic separation(More)