Xiaoli Cui

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The catecholaminergic neurotoxin 6-hydroxydopamine has been widely used to mimic the lesions in dopaminergic neurons to develop Parkinson’s disease. The present study was aimed to evaluate the combined treatment with Curcumin and desferrioxamine (DFO) on 6-OHDA- induced neurotoxicity in the striatum of rats. Rat models with 6-OHDA-induced Parkinson’s(More)
Clustering analysis is one of the most commonly used data processing algorithms. Over half a century, K-means remains the most popular clustering algorithm because of its simplicity. Recently, as data volume continues to rise, some researchers turn to MapReduce to get high performance. However, MapReduce is unsuitable for iterated algorithms owing to(More)
Deoxycytidine kinase (dCK) is a rate limiting enzyme critical for phosphorylation of endogenous deoxynucleosides for DNA synthesis and exogenous nucleoside analogues for anticancer and antiviral drug actions. dCK is activated in response to DNA damage; however, how it functions in the DNA damage response is largely unknown. Here, we report that dCK is(More)
The aim of this study was to investigate the association between diabetes mellitus (DM), mainly type II, with metabolic syndrome (MS) and diabetic nephrop-athy (DN)/diabetic retinopathy (DR). Based on the analysis of the prevalence of MS, patients with DM were divided into MS and non-MS groups according to the presence or absence of MS. The correlation(More)
Phage therapy requires the comprehensive understanding of the mechanisms underlying the host-phage interactions. In this work, to identify the genes related to Pseudomonas aeruginosa phage K8 receptor synthesis, 16 phage-resistant mutants were selected from a Tn5G transposon mutant library of strain PAK. The disrupted genetic loci were identified and they(More)
The underlying mechanisms of phage-host interactions largely remained to be elucidated. In this work, Pseudomonas aeruginosa phage C11 was first characterized as a Myoviridae virus having a linear dsDNA molecule of 94109 bp with 1173 bp identical terminal direct repeats (TDR). Then the mutants resistant to phage C11 were screened in a Tn5G transposon mutant(More)
ATIC, an enzyme involved in purine nucleotide biosynthesis anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive Updated information and services can be found at: (4217 articles) Neoplasia Articles on similar topics can be found in the following Blood collections Blood(More)
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