Xiaolan Chen

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With the explosive growth in data volume, the I/O bottleneck has become an increasingly daunting challenge for big data analytics. Economic forces, driven by the desire to introduce flash-based Solid-State Drives (SSDs) into the high-end storage market, have resulted in hybrid storage systems in the cloud. However, a single flash-based SSD cannot satisfy(More)
Chronic growth hormone (GH) therapy has been shown to cause insulin resistance, but the mechanism remains unknown. PTEN, a tumor suppressor gene, is a major negative regulator of insulin signaling. In this study, we explored the effect of chronic GH on insulin signaling in the context of PTEN function. Balb/c healthy mice were given recombinant human or(More)
Chrysin and its phosphate ester have previously been shown to inhibit cell proliferation and induce apoptosis in Hela cells; however, the underlying mechanism remains to be characterized. In the present study, we therefore synthesized diethyl flavon-7-yl phosphate (FP, C(19)H(19)O(6)P) by a simplified Atheron-Todd reaction, and explored its anti-tumor(More)
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