Xiaojing Shi

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OBJECTIVE Transgenic expression of diacylglycerol acyltransferase-1 (DGAT1) in skeletal muscle leads to protection against fat-induced insulin resistance despite accumulation of intramuscular triglyceride, a phenomenon similar to what is known as the "athlete paradox." The primary objective of this study is to determine how DGAT1 affects muscle fatty acid(More)
Intracellular lipid accumulation in the heart is associated with cardiomyopathy, yet the precise role of triglyceride (TG) remains unclear. With exercise, wild type hearts develop physiologic hypertrophy. This was associated with greater TG stores and a marked induction of the TG-synthesizing enzyme diacylglycerol (DAG) acyltransferase 1 (DGAT1). Transgenic(More)
Increased fat deposition in skeletal muscle is associated with insulin resistance. However, exercise increases both intramyocellular fat stores and insulin sensitivity, a phenomenon referred to as "the athlete's paradox". In this study, we provide evidence that augmenting triglyceride synthesis in skeletal muscle is intrinsically connected with increased(More)
High saturation magnetization monodisperse Fe(3)O(4) hollow microspheres (109.48 emu/g) with superparamagnetic property at room temperature are promptly synthesized by a one-step solvothermal process with the presence of sodium dodecylbenzenesulfonate as an additive. The as-synthesized products possess superparamagnetism, large cavity, high water(More)
Tert-butylhydroquinone (tBHQ), an inducer of nuclear factor erythroid 2-related factor 2 (Nrf2), has been demonstrated to attenuate oxidative stress-induced injury and the apoptosis of human neural stem cells and other cell types. However, whether tBHQ is able to exert a protective effect against oxidative stress and the apoptosis of cardiomyocytes has not(More)
A resonant microbeam accelerometer of a novel highly symmetric structure based on MEMS bulk-silicon technology is proposed and some numerical modeling results for this scheme are presented. The accelerometer consists of two proof masses, four supporting hinges, two anchors, and a vibrating triple beam, which is clamped at both ends to the two proof masses.(More)
Uniform silver hollow microcubes assembled by nanosheets have been synthesized by using Cu(2)O cubes as chemical template at room temperature. In the reaction system, the Ag(+) ions were reduced by Cu(+) ions released from Cu(2)O cubes, meanwhile the morphology of silver growth units were controlled by trisodium citrate in the form of nanosheets around the(More)