Xiaojie Chen

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BACKGROUND Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene transfer. During a routine surveillance project on antimicrobial resistance in commensal Escherichia coli from food animals in China, a major increase of colistin resistance was observed. When an E coli strain, SHP45, possessing(More)
To ascertain genetic diversity, population structure and linkage disequilibrium (LD) among a representative collection of Chinese winter wheat cultivars and lines, 90 winter wheat accessions were analyzed with 269 SSR markers distributed throughout the wheat genome. A total of 1,358 alleles were detected, with 2 to 10 alleles per locus and a mean genetic(More)
The impact of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae of food animal origins on human health has caught considerable attention worldwide. Intestinal Escherichia coli obtained from healthy food animals (pigs, cattle and poultry) in China were tested for the presence of ESBL genes. CTX-M-producing isolates were further characterised(More)
The aim of this study was to investigate the trends and the diversity of CTX-M types of extended-spectrum β-lactamase (ESBL) in Escherichia coli isolated from food animals in China over a ten-year period. From 2003 to 2012, 2815 E. coli isolates collected from diseased animals (chickens, pigs, and waterfowl) were screened for the prevalence of CTX-M genes.(More)
Dysregulation of NEAT1 plays critical oncogenic roles and facilitates tumorigenesis on various human tumor entities. However, little information is available about the expression pattern of NEAT1 in esophageal squamous cell carcinoma (ESCC). The contributions of this lncRNA to tumorigenesis and progression of ESCC aslo remains unclear. By performing(More)
We investigate two paradigms for studying the evolution of cooperation—Prisoner’s Dilemma and Snowdrift game in an online friendship network, obtained from a social networking site. By structural analysis, it is revealed that the empirical social network has small-world and scale-free properties. Besides, it exhibits assortative mixing pattern. Then, we(More)
We consider the coupled dynamics of the adaption of network structure and the evolution of strategies played by individuals occupying the network vertices. We propose a computational model in which each agent plays a n-round Prisoner’s Dilemma game with its immediate neighbors, after that, based upon self-interest, partial individuals may punish their(More)
Previous studies mostly assume deterministic interactions among neighboring individuals for games on graphs. In this paper, we relax this assumption by introducing stochastic interactions into the spatial Prisoner's dilemma game, and study the effects of interaction stochasticity on the evolution of cooperation. Interestingly, simulation results show that(More)
In the well-mixed prisoner's dilemma game, individuals are typically assumed to have no choice about whether to interact with other individuals in the population. In this paper, we instead consider reputation-based conditional interaction and its consequences for the evolution of cooperation. Each individual has a tolerance range, and only interacts with(More)
Increasing evidence suggests an association between cancer stem cells and the tumor microenvironment. Ovarian cancer stem cell (OCSC) factors can influence the tumor microenvironment and prognosis. However, the effects of OCSCs on macrophage M1/M2 polarization are not yet completely understood. In the present study, we evaluated the effects of OCSCs on(More)